Association of 25-hydroxyvitamin D with hematological profile and anthropometry in patients with glioma
Rev. Assoc. Med. Bras. (1992, Impr.)
;
68(11): 1547-1552, Nov. 2022. tab
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1406578
ABSTRACT
SUMMARY OBJECTIVE:
Gliomas are immune system suppressive tumors, and the role of vitamin D is pivotal in the immune system. This study aimed to observe if there is any significant association between the serum levels of 25-hydroxyvitamin D with hematological indices and anthropometric measurements.METHODS:
A total of 75 glioma patients were included, and the information was collected on gender, age group, area, socioeconomic status, intake of vitamin D and calcium in food and supplements, skin color, sunlight exposure, body mass index, and muscle strength. A nonparametric Kendall's tau-b correlation test was performed to find a correlation between 25-hydroxyvitamin D levels and blood counts, body mass index, and muscle strength.RESULTS:
The majority of patients (72%) were having low lymphocytes followed by high granulocytes and high white blood cells. The majority were having low levels of both 25-hydroxyvitamin D (84%) and calcium (73%). Patients were mainly from urban areas, and the majority belonged to middle-class families having sedentary lifestyles. The majority of patients were not taking vitamin D supplements. An insufficient amount of sunlight exposure was found in most of them. The majority of the patients were although had normal weight but weak muscle strength (74.6%). An insignificant correlation was found between 25-hydroxyvitamin D levels with the hematological indices or anthropometric measurements in brain tumor patients.CONCLUSION:
Vitamin D is a powerful immune modulator, and there is a great need for sufficient amounts of sunlight exposure and vitamin D-enriched diets to prevent cancer.
Full text:
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Index:
LILACS (Americas)
Type of study:
Risk factors
Language:
English
Journal:
Rev. Assoc. Med. Bras. (1992, Impr.)
Journal subject:
EducaÆo em Sa£de
/
GestÆo do Conhecimento para a Pesquisa em Sa£de
/
Medicine
Year:
2022
Type:
Article
Affiliation country:
Pakistan
Institution/Affiliation country:
National University of Computer and Emerging Sciences/PK
/
Punjab Institute of Neurosciences/PK
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