Evaluation of aversive behavior in Rattus norvegicus experimentally infected by two distinct strains of Toxoplasma gondii (ME49 and VEG): study of epigenetic markers
Rev. Soc. Bras. Med. Trop
;
55: e0122, 2022. graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1407005
ABSTRACT
ABSTRACT Background:
Behavioral changes in Rattus norvegicus infected with two strains of Toxoplasma gondii (ME49 and VEG) were investigated.Methods:
Rats were evaluated for motor activity and aversion or attraction to cat urine 60 days after infection. After euthanasia, arginine-vasopressin gene methylation in the central nervous system was evaluated.Results:
A significant difference was observed in the methylation of the arginine-vasopressin promoter gene between rats infected with the ME49 and VEG strains.Conclusions:
Although differences were not observed in many parameters, significant differences were observed in the methylation of the arginine-vasopressin promoter gene in rats infected with the two studied strains.
Full text:
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Index:
LILACS (Americas)
Language:
English
Journal:
Rev. Soc. Bras. Med. Trop
Journal subject:
Tropical Medicine
Year:
2022
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Santa Casa de São Paulo/BR
/
Universidade de São Paulo/BR
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