Actualización de resultados demográficos y terapéuticos de pacientes con Leucemia Mieloide Aguda no promielocítica en el Hospital Clínico de la Pontificia Universidad Católica de Chile / Acute myeloid leukemia. Analysis of 114 patients
Rev. méd. Chile
;
150(5): 643-649, mayo 2022.
Article
in Spanish
| LILACS
| ID: biblio-1409843
ABSTRACT
BACKGROUND:
Acute myeloid leukemia (AML) is the most common leukemia in adults.Aim:
To Describe our population of patients with AML and report the outcomes of our treatments. MATERIAL ANDMETHODS:
Review of electronic clinical records of 114 patients with AML with a median age of 57 years (59% men).Results:
Seventeen percent of patients were classified as low risk, 38% as intermediate risk and 33% as high risk. Seventy-six percent of patients were treated with intensive chemotherapy. Five years overall survival according to cytogenetic risk was 59, 41, and 12% in low, intermediate, and high-risk patients, respectively. The outcomes were better in patients under 60 years. The median survival of patients treated with intensive chemotherapy aged less than 60 years and 60 years and above was 3.4 and 1 year, respectively.CONCLUSIONS:
Our results are comparable to those reported in developed countries. Improving the survival of patients 60 years and older is our main challenge.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Leukemia, Myelomonocytic, Acute
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2022
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Red de Salud UC Christus/CL
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