Molecular detection of SARS-CoV-2 infection in three geo-political zones of Nigeria: a cross-sectional study
Pan Afr. med. j
;
44(NA): NA-NA, 2023.
Article
in English
| AIM
| ID: biblio-1419018
ABSTRACT
Introduction:
sequel to the emergence of the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) and its subsequent spread to all continents of the world, humans have continued to experience severe devastation to their health and economies. To control the spread of this virus, it is important to detect the infection in recently infected and asymptomatic individuals who are capable of infecting others. This study was designed to detect ongoing SARS-CoV-2 Infection among asymptomatic individuals in open markets across three geopolitical zones in Nigeria.Methods:
nasal and oropharyngeal swab samples were collected from 2,158 study participants between December 20th, 2020 and March 20th, 2021 from large open markets across three geo-political zones (Southwest, Northwest and Southeast) of Nigeria. Virus RNA was extracted from these swab samples and real time RT-PCR was carried out for the detection of SARS-CoV-2 specific genes. Data was analysed using descriptive statistics.Results:
a total of 163 (7.6%) of the 2,158 participants enrolled for the study tested positive for SARS-CoV-2 by RT-PCR. The rate of infection was significantly higher in the North-western states of the country when compared to the western and Eastern regions (P=0.000). Similarly, the rate of infection was higher among buyers than sellers (P=0.000) and among males when compared with females, though the difference was not significant (p=0.31).Conclusion:
this study shows that there is a continuous spread of SARS-CoV-2, especially among active, asymptomatic individuals across many states in the country. There is therefore need to continuously educate citizens on the need to adhere to both the non-pharmaceutical and pharmaceutical preventive measures to protect themselves and ultimately curb the spread of the virus.
Full text:
Available
Index:
AIM (Africa)
Main subject:
Diagnosis
/
SARS-CoV-2
/
COVID-19
Type of study:
Diagnostic study
/
Observational study
/
Prevalence study
Language:
English
Journal:
Pan Afr. med. j
Year:
2023
Type:
Article
Institution/Affiliation country:
Amino Kano University Teaching Hospital/NG
/
Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan/NG
/
Department of Health Promotion and Education, College of Medicine, University of Ibadan/NG
/
Department of Immunology, College of Medicine, University of Ibadan/NG
/
Department of Medical Microbiology and Parasitology, College of Medicine, University of Lagos/NG
/
Department of Microbiology, Ahmadu Bello University/NG
/
Department of Public Health, Ministry of Health/NG
/
Department of Virology, College of Medicine, University of Ibadan/NG
/
Ebonyi State Ministry of Health/NG
/
Federal University Teaching Hospital, Abakaliki/NG
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