Mini-Review of Poloxamer as a Biocompatible Polymer for Advanced Drug Delivery
Braz. J. Pharm. Sci. (Online)
; 58: e21125, 2022. tab, graf
Article
in En
|
LILACS-Express
| LILACS
| ID: biblio-1420373
Responsible library:
BR1.1
ABSTRACT
Abstract Poloxamer is a biocompatible polymer that has already been approved by the US FDA for multiple applications. Poloxamer itself has many grades and functional categories that enable the improvement of both physicochemical and biological properties of drugs. In this minireview, the functional properties of poloxamer for physicochemical modification, such as solubility and stability, and biological response modification, such as neuroprotection, cell apoptosis, efflux pump modification, membrane cell modification, and cellular uptake, are discussed to provide a broader understanding to assist the development of poloxamer-based formulations.
Full text:
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Index:
LILACS
Language:
En
Journal:
Braz. J. Pharm. Sci. (Online)
Journal subject:
Farmacologia
/
Teraputica
/
Toxicologia
Year:
2022
Type:
Article