Changes in the rest-activity rhythm in migraine patients are associated with anxiety symptoms
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
44(6): 611-620, Nov.-Dec. 2022. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1420518
ABSTRACT
Objective: To characterize rest-activity rhythm in chronic migraine (CM) and to investigate the relationship between this rhythm and depressive and anxiety symptoms in patients with CM. Methods: This was a study of adults aged 20 to 40 years. The rest-activity rhythm of patients with CM (n=23) and non-headache controls (NH, n=23) was assessed by actigraphy for 15 days, and they completed the following assessments: Visual Analogue Scale for pain intensity; Headache Diary; Headache Impact Test-6; Morningness-Eveningness Questionnaire; Pittsburgh Sleep Quality Index; Epworth Sleepiness Scale; Beck Depression Inventory; and State-Trait Anxiety Inventory. Results: Patients with CM showed less activity over 24 hours and more fragmented sleep. Reduced interdaily stability of the rest-activity rhythm was observed, with less robustness of this rhythm in the CM group. Multiple linear regressions revealed a significant association between the rest-activity rhythm and trait anxiety variables in patients with CM, specifically regarding the relative amplitude of the cycle, activity throughout 24 hours and during sleep, and robustness of the rest-activity rhythm. Conclusions: Our findings provide evidence that the robustness of the rest-activity rhythm, activity throughout 24 hours, and sleep fragmentation are associated with trait anxiety in patients with CM. Clinical trial registration: Brazilian Clinical Trials Registry (registration number: RBR-4M5J4S).
Full text:
Available
Index:
LILACS (Americas)
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Risk factors
Language:
English
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
Psychiatry
Year:
2022
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Centro Universitário UNIFACISA/BR
/
UEPB/BR
/
Universidade Estadual da Paraíba (UEPB)/BR
/
Universidade Federal da Paraíba (UFPB)/BR
/
Universidade Federal de Pernambuco (UFPE)/BR
/
Universidade Federal do Rio Grande do Norte (UFRN)/BR
Similar
MEDLINE
...
LILACS
LIS