Impact of topical airway anesthesia on immediate postoperative cough/bucking: a systematic review and meta-analysis
Braz. J. Anesth. (Impr.)
;
73(1): 91-100, Jan.-Feb. 2023. tab, graf
Article
in English
| LILACS
| ID: biblio-1420641
ABSTRACT
Abstract Background Postoperative cough may occur after tracheal intubation, but it is indistinct which drug is best at diminishing these events. Additionally, airway reflexes are commonly accompanied by severe hemodynamics responses during emergence. Objectives To evaluate the role of topical airway anesthesia on immediate post-extubation cough/bucking and extubation time. Methods Randomized clinical trials from MEDLINE, EMBASE, CENTRAL, and LILACS published until December 23, 2020 were included. Our primary outcome was postoperative cough/bucking incidence which was compared between local anesthetics and controls. Extubation times were likewise considered. Predisposition appraisal and subgroup, affectability investigations were likewise performed. Results The pooled analysis found a 45% reduction in cough incidence after treatment with topical airway local anesthetic (RR = 0.55; 95% CI 0.42 to 0.72; p< 0.001). The number needed to treat (NNT) was 4.61. The intervention showed no differences in reduction of the extubation time (mean difference = -0.07; 95% CI -0.14 to 0.28; p= 0.49). Conclusion Topical airway anesthesia demonstrated better than placebo or no medication in reducing immediate post-extubation cough/bucking. Further studies could have this objective to combine the different ways to perform better outcomes for patients.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Cough
/
Intubation, Intratracheal
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Systematic reviews
Limits:
Humans
Language:
English
Journal:
Braz. J. Anesth. (Impr.)
Year:
2023
Type:
Article
Affiliation country:
Brazil
/
United States
Institution/Affiliation country:
Clinigastro Medicina Integrada/BR
/
Harvard Medical School/US
/
Universidade de São Paulo/BR
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