A meta-analysis of the effect of Sjögren′s syndrome on adverse pregnancy outcomes
Clinics
;
77: 100140, 2022. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1421234
ABSTRACT
Abstract Objective This study aimed to assess the correlation between Sjögren′s Syndrome (SS) and adverse pregnancy outcomes, with the aim of providing a basis for preconception and pregnancy interventions in women with SS. Methods A search of electronic databases in English and Chinese databases from January 2005 to December 2021, was conducted to collect the literature of case-control studies or cohort studies on the association between SS and pregnancy outcome studies. Literature inclusion and data extraction were performed according to established criteria, and the Newcastle-Ottawa scale was used to evaluate the quality of the literature. Stata 15 software was used for meta-analysis. Results A total of nine papers were included in this study. Meta-analysis results showed that SS was associated with spontaneous abortion (RR = 8.85, 95% CI 3.10‒25.26), preterm birth (RR = 2.27, 95% CI 1.46‒3.52), low birth mass (RR = 1.99, 95% CI 1.34‒2.97), and birth defects (RR = 4.28, 95% CI 3.08‒5.96). Conclusion SS can increase the incidence of adverse pregnancy outcomes.
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Index:
LILACS (Americas)
Type of study:
Observational study
/
Risk factors
/
Systematic reviews
Language:
English
Journal:
Clinics
Journal subject:
Medicine
Year:
2022
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
University of Chinese Academy of Sciences/CN
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