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Infiltrating mammary carcinoma in a cat with a congenital disorder: prognostic interest of histological examination / Carcinoma mamario infiltrante en una gata con un trastorno congénito: interés pronóstico del examen histológico
Hadef, Ahmed; Hamlaoui, Mohamed Walid; Bougherara, Hithem; Haouar, Lamine.
  • Hadef, Ahmed; Department of veterinary sciences, Faculty of nature and life sciences, Chadli Bendjedid University of El Tarf - Laboratory of Development and Control of Hospital Pharmaceutical Preparations, Faculty of Medicine, Badji Mokhtar University of Annaba. DZ
  • Hamlaoui, Mohamed Walid; Laboratory of Development and Control of Hospital Pharmaceutical Preparations, Faculty of Medicine, Badji Mokhtar University of Annaba - Institute of Veterinary Sciences, Frères Mentouri University of Constantine, El Khroub. DZ
  • Bougherara, Hithem; Institute of Veterinary Sciences, Frères Mentouri University of Constantine, El Khroub. DZ
  • Haouar, Lamine; DMV, veterinary practitioner. DZ
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1421453
RESUMEN
Resumen En esta publicación se describe el manejo y la evolución clínica de un carcinoma mamario felino (CMF) maligno en una gata mestiza de ocho años de edad con un trastorno congénito. La eficacia de la extirpación de la masa tumoral y el pronóstico del caso se establecieron mediante el examen histológico de rutina postoperatorio. Tras una mastectomía completa se extirpó un bulto de 6 cm de diámetro en la glándula mamaria torácica izquierda de aspecto multinodular y exudado purulento de coloración rojiza. El análisis histopatológico mostró la presencia de numerosos émbolos tumorales linfovasculares y células con alta frecuencia de figuras mitóticas con núcleos hipercromáticos. Estos hallazgos fueron consistentes con una neoplasia agresiva de mal pronóstico, lo que explicaba el fallecimiento de la paciente a las 7 semanas de la cirugía. Los hallazgos histológicos y citológicos son de importancia crítica para los clínicos en el manejo de las neoplasias mamarias más comunes en los gatos, con el fin de aliviar de la mejor manera posible a los animales con cánceres que amenazan su vida. También podría servir como modelo de cáncer para avanzar en el conocimiento de patologías similares en otras especies.
ABSTRACT
Abstract This report describes the handling and clinical evolution of a malignant feline mammary carcinoma (FMC) in an eight-year-old female crossbred cat with a congenital disorder. Hence, the efficacy of tumor mass removal and the case prognosis was established by postoperative routine histological examination. A 6 cm diameter lump in the left thoracic mammary gland of multinodular appearance and purulent exudate with a reddish hue was excised after the entire mastectomy. The histopathological analysis showed the presence of numerous lymphovascular tumor emboli and frequently mitotic cells with hyperchromatic nuclei. These were consistent with an aggressive malignancy with a poor prognosis explaining the patient's death within 7 weeks after surgery. Histology and cytology findings are of critical importance to clinicians in the management of the most common mammary malignancies in cats, to provide the best possible relief to animals with life-threatening cancer. It could also serve as a cancer model for advancing knowledge in congenitally affected humans.


Full text: Available Index: LILACS (Americas) Type of study: Prognostic study Language: Spanish Journal: FAVE, Secc. Cienc. vet. (En línea) Journal subject: Cria‡Æo de Animais Dom‚sticos / Cruzamento / Gado Year: 2022 Type: Article Affiliation country: Algeria Institution/Affiliation country: DMV, veterinary practitioner/DZ / Department of veterinary sciences, Faculty of nature and life sciences, Chadli Bendjedid University of El Tarf - Laboratory of Development and Control of Hospital Pharmaceutical Preparations, Faculty of Medicine, Badji Mokhtar University of Annaba/DZ / Laboratory of Development and Control of Hospital Pharmaceutical Preparations, Faculty of Medicine, Badji Mokhtar University of Annaba - Institute of Veterinary Sciences, Frères Mentouri University of Constantine, El Khroub/DZ

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Full text: Available Index: LILACS (Americas) Type of study: Prognostic study Language: Spanish Journal: FAVE, Secc. Cienc. vet. (En línea) Journal subject: Cria‡Æo de Animais Dom‚sticos / Cruzamento / Gado Year: 2022 Type: Article Affiliation country: Algeria Institution/Affiliation country: DMV, veterinary practitioner/DZ / Department of veterinary sciences, Faculty of nature and life sciences, Chadli Bendjedid University of El Tarf - Laboratory of Development and Control of Hospital Pharmaceutical Preparations, Faculty of Medicine, Badji Mokhtar University of Annaba/DZ / Laboratory of Development and Control of Hospital Pharmaceutical Preparations, Faculty of Medicine, Badji Mokhtar University of Annaba - Institute of Veterinary Sciences, Frères Mentouri University of Constantine, El Khroub/DZ