Erosive Effect of Analgesics on Primary Tooth Enamel - An in Vitro Study
Pesqui. bras. odontopediatria clín. integr
;
22: e210149, 2022. tab, graf
Article
in English
| LILACS, BBO
| ID: biblio-1422256
ABSTRACT
Abstract Objective:
To evaluate in vitro erosive effect of analgesics on primary tooth enamel. Material andMethods:
The pH and the titratable acidity measurements of the medicines were performed in triplicate using a digital pH meter. Enamel slabs of primary teeth flat and polished were selected by initial surface microhardness analysis. Medications were selected and specimens were assigned into five groups (n=12) Dalsy; Magnopyrol; Paracetamol; Tylenol; and distilled water (negative control). Specimens were immersed in 5 ml of each group solution for 30 min, 4x/day for three days and stored in artificial saliva at 37 °C between immersions and at night. Final microhardness was determined. The data were submitted to Oneway ANOVA and Tukey's test. Scanning electron microscopy (SEM) analysis was performed in three specimens of each group.Results:
Medicines showed acidic pH and mean values of titratable acidity ranged from 1.46 to 11.66 ml of 0.1N NaOH. The mineral loss of Magnopyrol was statistically significant in relation to the control group (p<0.01). Magnopyrol showed higher values when compared to Tylenol (p<0.05). SEM images displayed microstructure alterations in the Paracetamol group.Conclusion:
Despite the low pH values, only Magnopyrol showed greater enamel softening. Paracetamol demonstrated morphological changes in primary tooth enamel (AU).
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Tooth, Deciduous
/
Tooth Erosion
/
Dental Enamel
/
Analgesics
Type of study:
Evaluation studies
Limits:
Humans
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2022
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Ceará/BR
Similar
MEDLINE
...
LILACS
LIS