Can Hemophilia Impact on the Oral Health Conditions of Children and Adolescents? A Systematic Review and Metanalysis
Pesqui. bras. odontopediatria clín. integr
;
22: e210152, 2022. tab, graf
Article
in English
| LILACS, BBO
| ID: biblio-1422289
ABSTRACT
Abstract Objective:
To analyze if the oral health conditions in children and adolescents are associated with hemophilia (PROSPERO-42020168192). Material andMethods:
The search strategy was performed in PubMed, Scopus, Lilacs/BBO, Web of Science, Cochrane, and Grey literature databases. Two independent researchers assessed the risk of bias in these studies by the Newcastle-Ottawa Scale. For the meta-analysis, the clinical conditions data were extracted as numerical variables according to their indexes, such as dental caries experience (dmft/DMFT), gingival condition (Modified Gingival Index - IGM), and oral hygiene (Plaque Index - PI). The quality of the evidence of the meta-analysis was evaluated by the GRADE tool (GRADEproGDT).Results:
From a total of 431 studies, 27 were included, and 10 were included in the meta-analysis. The studies presented a moderate risk of bias, ranging from 2 to 7 points. The dental caries experience in primary (-0.62; CI95% -1.68-0.43) and permanent dentitions (-0.05; CI95% -0.69-0.59), gingival condition (-0.12; CI95% -0.27-0.03), and oral hygiene (0.36; CI95% -0.06-0.77) did not differ between the groups.Conclusion:
Based on studies with very weak evidence, there were no differences in the oral health conditions of children and adolescents with and without hemophilia (AU).
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Oral Hygiene
/
Child
/
Oral Health
/
Adolescent
/
Hemophilia A
Type of study:
Systematic reviews
Limits:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Infant, Newborn
Language:
English
Journal:
Pesqui. bras. odontopediatria clín. integr
Journal subject:
Dentistry
Year:
2022
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of Paraná/BR
/
State University of Ponta Grossa/BR
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