Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil
J. venom. anim. toxins incl. trop. dis
;
19: 1-3, maio 2013.
Article
in English
| LILACS, VETINDEX
| ID: biblio-1484527
ABSTRACT
Brazil holds annual nationwide public campaigns to vaccinate dogs and cats against rabies. The presence of rabies antibodies in these animals, which are among the main transmitters of rabies to humans, is a good indicator that they are immunized and protected.Methods In the present study we analyzed 834 serum samples from dogs and cats from the Southeast of Brazil (Presidente Prudente and Dracena cities), 12 months after the 2009 vaccination campaign. We used the technique known as rapid fluorescent focus inhibition test (RFFIT) and considered reactant those sera with values higher 0.5 IU/mL. Results and discussion Reactant sample results in Presidente Prudente were 153 (51.0%) for dogs and 59 (32.6%) for cats, and in Dracena 110 (52.1%) for dogs and 71 (50.0%) for cats. We discussed vaccine coverage of animals involved in this experiment, and observed low titers < 0.5 IU/mL, especially in cats from Presidente Prudente.Conclusion According to the results presented in our experiment, we suggest that titers below 0.5 IU/mL are worrisome and that, for multiple reasons, animals should be immunized against rabies in the period between public vaccination campaigns. Hence, the desired vaccine coverage was not accomplished, especially among cats from Presidente Prudente.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Rabies
/
Vaccination
/
Immune System
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
J. venom. anim. toxins incl. trop. dis
Year:
2013
Type:
Article
Institution/Affiliation country:
São Paulo Agency for Agribusiness Technology/BR
/
São Paulo State University/BR
/
Zoonosis Control Center/BR
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