Association among H. pylori virulence markers dupA, cagA and vacA in Brazilian patients
J. venom. anim. toxins incl. trop. dis
;
20: 1-5, 04/02/2014. tab
Article
in English
| LILACS, VETINDEX
| ID: biblio-1484565
ABSTRACT
Only a few Helicobacter pylori-infected individuals develop severe gastric diseases and virulence factors of H. pylori appear to be involved in such clinical outcomes. Duodenal ulcer promoting gene A (dupA) is a novel virulence factor of Helicobacter pylori that is associated with duodenal ulcer development and reduced risk for gastric carcinoma in some populations. The aims of the present study were to determine the presence of dupA gene and evaluate the association among dupA and other virulence factors including cagA and vacA in Brazilian patients. Gastric biopsies were obtained from 205 dyspeptic patients (100 children and 105 adults). DNA was extracted and analyzed for the presence of H. pylori and its virulence factors using the polymerase chain reaction method.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Peptic Ulcer
/
Virulence
/
Helicobacter pylori
Type of study:
Risk factors
Limits:
Animals
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
J. venom. anim. toxins incl. trop. dis
Year:
2014
Type:
Article
Institution/Affiliation country:
Universidade do Sagrado Coração/BR
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