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Detection and identification of huwentoxin-IV interacting proteins by biotin-avidin chemistry combined with mass spectrometry
Yu, Hai; Liu, Hui; yan, Yizhong; Duan, Zhigui; Wang, Xianchun.
  • Yu, Hai; Universidade de Hunan Normal. Faculdade de Ciências Biológicas. Changsha. CN
  • Liu, Hui; Universidade de Hunan Normal. Faculdade de Ciências Biológicas. Changsha. CN
  • yan, Yizhong; Universidade de Hunan Normal. Faculdade de Ciências Biológicas. Changsha. CN
  • Duan, Zhigui; Universidade de Hunan Normal. Faculdade de Ciências Biológicas. Changsha. CN
  • Wang, Xianchun; Universidade de Hunan Normal. Faculdade de Ciências Biológicas. Changsha. CN
Article in English | LILACS, VETINDEX | ID: biblio-1484574
ABSTRACT
Numerous spider toxins are of interest as tools for neurophysiological research or as lead molecules for the development of pharmaceuticals and insecticides. Direct detection and identification of the interacting proteins of a spider toxin are helpful for its action-mechanism analysis and practical application. The present study employed a combinative strategy for the analysis of interacting proteins of huwentoxin-IV (HWTX-IV), a peptidic neurotoxin from the venom of the spider Selenocosmia huwena.
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Spectrum Analysis / Spiders / Avidin / Animals, Poisonous Type of study: Diagnostic study Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Year: 2014 Type: Article Institution/Affiliation country: Universidade de Hunan Normal/CN

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Full text: Available Index: LILACS (Americas) Main subject: Spectrum Analysis / Spiders / Avidin / Animals, Poisonous Type of study: Diagnostic study Limits: Animals Language: English Journal: J. venom. anim. toxins incl. trop. dis Year: 2014 Type: Article Institution/Affiliation country: Universidade de Hunan Normal/CN