Comorbidity patterns and mortality among hospitalized patients with psychiatric disorders and COVID-19
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
;
45(4): 327-333, Aug. 2023. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1513819
ABSTRACT
Objectives:
To examine the association between psychiatric and non-psychiatric comorbidity and 28-day mortality among patients with psychiatric disorders and COVID-19.Methods:
Multicenter observational retrospective cohort study of adult patients with psychiatric disorders hospitalized with laboratory-confirmed COVID-19 at 36 Greater Paris university hospitals (January 2020-May 2021) (n=3,768). First, we searched for different subgroups of patients according to their psychiatric and non-psychiatric comorbidities through cluster analysis. Next, we compared 28-day all-cause mortality rates across the identified clusters, while taking into account sex, age, and the number of medical conditions.Results:
We found five clusters of patients with distinct psychiatric and non-psychiatric comorbidity patterns. Twenty-eight-day mortality in the cluster of patients with mood disorders was significantly lower than in other clusters. There were no significant differences in mortality across other clusters.Conclusion:
All psychiatric and non-psychiatric conditions may be associated with increased mortality in patients with psychiatric disorders and COVID-19. The lower risk of death among patients with mood disorders might be in line with the potential beneficial effect of certain antidepressants in COVID-19, but requires further research. These findings may help identify at-risk patients with psychiatric disorders who should benefit from vaccine booster prioritization and other prevention measures.
Full text:
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Index:
LILACS (Americas)
Language:
English
Journal:
Braz. J. Psychiatry (São Paulo, 1999, Impr.)
Journal subject:
Psychiatry
Year:
2023
Type:
Article
Affiliation country:
France
/
Spain
Institution/Affiliation country:
Assistance Publique-Hôpitaux de Paris, Hôpital Corentin-Celton/FR
/
Universidad Complutense de Madrid, Campus de Somosaguas/ES
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