The prognostic value of peripheral blood parameters on all-frequency sudden sensorineural hearing loss
Braz. j. otorhinolaryngol. (Impr.)
;
89(5): 101302, Sept.-Oct. 2023. tab, graf
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1520489
ABSTRACT
Abstract Objective:
To determine whether peripheral blood parameters have any predictive value for all-frequency Sudden Sensorineural Hearing Loss (SSNHL).Methods:
We chose 78 individuals with all-frequency SSNHL who had been admitted to our department. They were divided into two groups the effective group and the ineffective group. In patients with all-frequency SSNHL, the prognostic variables, including peripheral blood tests and clinical traits, were examined by a logistic regression analysis. In addition, the predictive value was carried out.Results:
The effective rate of all-frequency SSNHL was 61.5%. Pre-treatment hearing level and the proportion of patients with diabetes were both significantly lower in the effective group than in the ineffective group (p = 0.024 and 0.000, respectively). The levels of fibrinogen and C-reactive protein were also significantly different between the two groups (p = 0.001 and 0.025, respectively). Pre-treatment hearing level and fibrinogen level both significantly impacted the prognosis of all-frequency SSNHL (p = 0.032 and 0.002, respectively), according to a logistic regression analysis. Furthermore, the prognosis was significantly predicted by both fibrinogen level and pre-treatment hearing level (p = 0.001 and 0.0002, respectively). The receiver operating characteristic curve showed that the fibrinogen level had a sensitivity of 85.4% and a specificity of 60.0% for predicting the prognosis of all-frequency SSNHL.Conclusion:
For the prognosis of all-frequency SSNHL, the fibrinogen level can be regarded as a useful predictor. The level of C-reactive protein, however, does not have a significant prognostic effect on predicting all-frequency SSNHL. Therefore, more attention should be devoted to the level of fibrinogen in the acute period of all-frequency SSNHL. Level of Evidence 4.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
Braz. j. otorhinolaryngol. (Impr.)
Journal subject:
Otolaryngology
Year:
2023
Type:
Article
Affiliation country:
China
Institution/Affiliation country:
The Affiliated Peoples Hospital of Ningbo University/CN
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