Relevancia y prevalencia de los parámetros histopatológicos y subtipos moleculares del cáncer de mama en mujeres del área costera de Ecuador atendidas en una institución de Salud Pública / Prevalence and significance of breast cancer pathologycal subtypes in Ecuador
Rev. méd. Chile
;
151(2): 170-176, feb. 2023. tab
Article
in Spanish
| LILACS
| ID: biblio-1522080
ABSTRACT
BACKGROUND:
The success of breast cancer (BC) treatment depends largely on the clinical-histological characteristics of the patient. Immunohistochemical (IHC) Breast Cancer Subtypes are crucial for therapeutic purposes.AIM:
To determine the relevance and prevalence of the histopathological parameters and molecular subtypes of BC among women attending public health services. MATERIAL ANDMETHODS:
A retrospective cross-sectional study was carried out in 199 female patients with histopathological diagnosis of breast cancer, treated at a Guayaquil city hospital in Ecuador, from January 2014 to December 2017.RESULTS:
Luminal A carcinoma was the most prevalent tumor in the studied women (54%). Thirty seven percent of patients did not have nodal involvement, 40% had one to three lymph nodes involved and 2% had 10 or more nodes involved. Most patients had a tumor size > 2 and ≤ 5 cm (72%) and moderately differentiated specifications (57%).CONCLUSIONS:
The study allowed the characterization of breast cancer according to the prevalence of molecular subtypes and clinical and histological characteristics. These factors determine therapeutic behaviors that optimize the use of the limited resources of the Public Health System.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Breast Neoplasms
/
Carcinoma
Limits:
Female
/
Humans
Country/Region as subject:
South America
/
Ecuador
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2023
Type:
Article
Affiliation country:
Ecuador
/
Spain
Institution/Affiliation country:
Universidad Camilo José Cela/ES
/
Universidad Técnica del Norte/EC
/
Universidad de Especialidades Espíritu Santo/EC
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