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Spongiform leukoencephalopathy unveiled in an autopsy of a drug abuser
Jangir, Hemlata; Balmuchu, Govinda; Mylapalli, Jhansi Lakshmi; Subramanian, Arulselvi; Lalwani, Sanjeev.
  • Jangir, Hemlata; All India Institute of Medical Sciences. Jai Prakash Narayan Apex Trauma Centre. Department of Laboratory Medicine. New Delhi. IN
  • Balmuchu, Govinda; All India Institute of Medical Sciences. Jai Prakash Narayan Apex Trauma Centre. Department of Forensic Pathology and Molecular DNA. New Delhi. IN
  • Mylapalli, Jhansi Lakshmi; All India Institute of Medical Sciences. Jai Prakash Narayan Apex Trauma Centre. Department of Forensic Pathology and Molecular DNA. New Delhi. IN
  • Subramanian, Arulselvi; All India Institute of Medical Sciences. Jai Prakash Narayan Apex Trauma Centre. Department of Laboratory Medicine. New Delhi. IN
  • Lalwani, Sanjeev; All India Institute of Medical Sciences. Jai Prakash Narayan Apex Trauma Centre. Department of Forensic Pathology and Molecular DNA. New Delhi. IN
Autops. Case Rep ; 13: e2023465, 2023. graf
Article in English | LILACS-Express | LILACS | ID: biblio-1527933
ABSTRACT
ABSTRACT Toxic leukoencephalopathy (TLE) is a rare neurological debilitating and fatal condition. It has been previously associated with exposure to leukotoxic offenders such as chemotherapy, cranial radiation, certain drugs, and environmental factors. Currently, it is a commoner white matter syndrome resulting from increased substance abuse, classically by inhaled heroin and other opioids. Herein, we report a case of fatal TLE unveiled in an autopsy of a drug abuser. A 24-year-old male was found dead on the roadside. A day before, he was located in a state of delirium. In this case, the autopsy findings and histopathology characteristics of cerebral cortex involvement particularly directed to speculate the heroine as the principal offender.

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Full text: Available Index: LILACS (Americas) Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2023 Type: Article Affiliation country: India Institution/Affiliation country: All India Institute of Medical Sciences/IN

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Full text: Available Index: LILACS (Americas) Language: English Journal: Autops. Case Rep Journal subject: Anatomia / Patologia Cl¡nica / Patologia Legal Year: 2023 Type: Article Affiliation country: India Institution/Affiliation country: All India Institute of Medical Sciences/IN