Non-Invasive Study of Intracranial Pressure in Pre- and Post-Chemotherapy Patients for the Treatment of Breast Neoplasia
ABCS health sci
;
48: [1-7], 14 fev. 2023.
Article
in English
|
LILACS-Express
| LILACS
| ID: biblio-1537363
ABSTRACT
Introduction:
Breast cancer is the most common type among women and brings to them significant organic changes. A new intracranial pressure monitorization method consists of an external system of sensors that detects micrometric deformations on the cranial bones and transmits, in real-time, electrical signals that are visualized on a monitor.Objective:
To identify changes in intracranial pressure due to chemotherapy connections through non-invasive methodology.Methods:
The present study was conducted at Hospital Santa Casa de Misericordia in the city of Ponta Grossa, PR, Brazil in 2017. The variables P2/P1 ratio (ICP morphological evaluation), laboratory parameters, comorbidities, and clinical aspects of the volunteers were evaluated. The vascular toxicity of chemotherapy often causes endothelial dysfunction, resulting in a loss of vasodilation effects and suppresses anti-inflammatory and vascular repair functions.Results:
The values of the P2/P1 ratio before and after chemotherapy were also compared between groups. A statistically significant difference was observed in the pre chemotherapy P2/P1 values compared to the post-chemotherapy values.Conclusion:
Variations in ICP may occur in cancer patients. Further studies are necessary to evaluate if this change may contribute to the chemotherapy side effects occurrence.
Full text:
Available
Index:
LILACS (Americas)
Language:
English
Journal:
ABCS health sci
Journal subject:
Medicine
/
Public Health
Year:
2023
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Braincare Desenvolvimento e Inovação Tecnológica S.A/BR
/
Universidade Estadual de Ponta Grossa/BR
Similar
MEDLINE
...
LILACS
LIS