Monkeypox and chickenpox co-infection in a person living with Human Immunodeficiency Virus
J. infect. dev. ctries
;
18(7): 1152-1156, 2024. figures, tables
Article
in English
| AIM
| ID: biblio-1566043
ABSTRACT
Introduction:
The 2022 mpox global outbreak underscores the need for an improved understanding of mpox epidemiology, co-morbidities, and clinical management/outcome. We report a case of a30-year-old Nigerian antiretroviral treatment-experienced person living with human immunodeficiency virus (PLHIV) who had PCR-confirmed mpox and chickenpox co-infection. Case presentation The patient presented with a generalized itchy rash of three weeks and antecedent low-grade fever. He had no recent travel, animal exposure, or same-sex relationship. Examination revealed generalized pustular and nodular eruptions without peripheral lymphadenopathy.Results:
CD4 count was 78 cells/mm3, wound swab microscopy revealed Gram-positive cocci in clusters and Gram-negative bacilli while culture yielded Pseudomonas aeruginosa. Despite supportive care and definitive antimicrobial therapy, his clinical condition deteriorated with sepsis-related multi-organ dysfunction and ultimately death.Conclusions:
Mpox and chickenpox co-infection may occur, with potentially fatal complications in the setting of advanced HIV disease. Increased surveillance for co-viral infections in PLHIV with febrile exanthema and aggressive management to improve outcome are recommended.Subject(s)
Full text:
Available
Index:
AIM (Africa)
Main subject:
HIV Infections
/
Coinfection
Language:
English
Journal:
J. infect. dev. ctries
Year:
2024
Type:
Article
Institution/Affiliation country:
Department of Internal Medicine, Federal Medical Centre, Owerri, Imo State, Nigeria/NG
/
Ozalla, Enugu, Nigeria+NG
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