Fixed drug eruption by etoricoxib confirmed by patch test
An. bras. dermatol
;
91(5): 652-654, Sept.-Oct. 2016. graf
Article
in English
| LILACS
| ID: biblio-827762
ABSTRACT
Abstract Non-steroidal, anti-inflammatory drugs, followed by antibiotics, are the main causes of fixed drug eruption. They provoke one or several round erythematous or bullous lesions that recur in the same place after taking the causative medication. A positive patch test on residual, lesional skin can replace satisfactorily oral reintroduction. We describe the case of a 74-year-old woman with numerous, rounded, erythematous lesions on the trunk and recurrent blistering on the fifth right-hand finger, which developed a few hours after taking etoricoxib. Lesional patch testing with etoricoxib was positive and reproduced the typical pattern of a fixed drug eruption upon histopathology. We emphasize the specific reactivity of the etoricoxib patch test, and the capacity to reproduce the histologic pattern of the reaction.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Pyridines
/
Sulfones
/
Patch Tests
/
Drug Eruptions
/
Cyclooxygenase 2 Inhibitors
Limits:
Aged
/
Female
/
Humans
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2016
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Complexo Hospitalar Padre Bento de Guarulhos/BR
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