Abacavir-induced liver toxicity
Braz. j. infect. dis
;
20(5): 502-504, Sept.-Oct. 2016.
Article
in English
| LILACS
| ID: biblio-828150
ABSTRACT
Abstract Abacavir-induced liver toxicity is a rare event almost exclusively occurring in HLA B*5701-positive patients. Herein, we report one case of abnormal liver function tests occurring in a young HLA B*5701-negative woman on a stable nevirapine-based regimen with no history of liver problems or alcohol abuse after switching to abacavir from tenofovir. We also investigated the reasons for abacavir discontinuation in a cohort of patients treated with abacavir-lamivudine-nevirapine.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Dideoxynucleosides
/
Anti-HIV Agents
/
Antiretroviral Therapy, Highly Active
/
Chemical and Drug Induced Liver Injury
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Braz. j. infect. dis
Journal subject:
Communicable Diseases
Year:
2016
Type:
Article
Affiliation country:
Italy
Institution/Affiliation country:
Università di Milano/IT
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