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The role of the mean platelet volume and neutrophil-to-lymphocyte ratio in peritonsillar abscesses / O papel do volume plaquetário médio e a relação neutrófilos/linfócitos em abscesso periamigdaliano
Şentürk, Mehmet; Azgın, İsa; Övet, Gültekin; Alataş, Necat; Ağırgöl, Betül; Yılmaz, Esra.
  • Şentürk, Mehmet; Konya Education and Research Hospital. Department of Otolaryngology Head and Neck Surgery. Konya. TR
  • Azgın, İsa; Konya Education and Research Hospital. Department of Otolaryngology Head and Neck Surgery. Konya. TR
  • Övet, Gültekin; Konya Education and Research Hospital. Department of Otolaryngology Head and Neck Surgery. Konya. TR
  • Alataş, Necat; Konya Education and Research Hospital. Department of Otolaryngology Head and Neck Surgery. Konya. TR
  • Ağırgöl, Betül; Konya Education and Research Hospital. Department of Otolaryngology Head and Neck Surgery. Konya. TR
  • Yılmaz, Esra; Konya Education and Research Hospital. Department of Otolaryngology Head and Neck Surgery. Konya. TR
Braz. j. otorhinolaryngol. (Impr.) ; 82(6): 662-667, Oct.-Dec. 2016. tab, graf
Article in English | LILACS | ID: biblio-828248
ABSTRACT
Abstract

Introduction:

Peritonsillar abscess is a serious infectious disease of the tonsillar tissue. Treatment generally requires both medical and surgical approaches to relieve the symptoms. Recently, in addition to clinical follow-up, some inflammatory markers, such as the mean platelet volume and neutrophil-to-lymphocyte ratio, have been considered to be additional inflammatory monitoring markers in inflammatory diseases.

Objective:

The aim of this study was to describe the role of mean platelet volume and neutrophil-to-lymphocyte ratio in patients with peritonsillar abscess.

Methods:

A retrospective study was conducted in 88 patients with peritonsillar abscess and 88 healthy individuals. We analyzed the white blood cell count, neutrophil count, lymphocyte count, platelet count, C-reactive protein, mean platelet volume and neutrophil-to-lymphocyte ratio values and compared them among the patient and control groups.

Results:

The mean platelet volume levels were significantly higher in the peritonsillar abscess pretreatment group than in the peritonsillar abscess posttreatment group and the control group. A mean platelet volume value of 8.7 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 75%, 65.9%, 68% and 72%, respectively. The neutrophil-to-lymphocyte ratio levels were significantly higher in the peritonsillar abscess pretreatment group than in the peritonsillar abscess post-treatment group and the control group. A neutrophil-to-lymphocyte ratio value of 3.08 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 90.9%, 90.9%, 90.9% and 90.9%, respectively. While the white blood cell count, neutrophil count, lymphocyte count and C-reactive protein values were significantly different among the patient and control groups (p < 0.05), the platelet count was not significantly different among the patient and control groups (p > 0.05).

Conclusion:

The mean platelet volume and neutrophil-to-lymphocyte ratio values made us think that these parameters were quick, inexpensive and reliable inflammatory follow-up parameters and could be easily integrated into daily practice for peritonsillar abscess treatment except platelet count.
RESUMO
Resumo

Introdução:

O abscesso periamigdaliano (APA) é uma doença infecciosa grave do tecido tonsilar. O seu tratamento geralmente requer uma abordagem medicamentosa e cirúrgica para o alívio dos sintomas. Recentemente, além do acompanhamento clínico, alguns marcadores inflamatórios, como o volume plaquetário médio (VPM) e a relação neutrófilos/linfócitos (RN/L), foram considerados marcadores de monitoramento adicionais em doenças inflamatórias.

Objetivo:

O objetivo deste estudo foi descrever o papel os VPM e a RN/L em pacientes com APA.

Método:

Estudo retrospectivo realizado com 88 pacientes com ATP e 88 indivíduos saudáveis. Analisamos a contagem de leucócitos, neutrófilos, linfócitos, plaquetas, proteína C-reativa (PCR), VPM e RN/L e a comparamos os valores entre o grupo de pacientes e grupo controle.

Resultados:

Os níveis de VPM eram significativamente maiores no grupo APA pré-tratamento que no grupo APA pós-tratamento e no grupo controle. Um valor de corte de 8,7 para o VPM foi considerado ideal para avaliar sensibilidade, especificidade, valor preditivo positivo e valor preditivo negativo de 75, 65,9, 68 e 72%, respectivamente. Os níveis da RN/L eram significantemente maiores no grupo APA pré-tratamento que no grupo APA pós-tratamento e no grupo controle. Um valor de 3,08 para a RN/L foi o valor de corte ideal para avaliar sensibilidade, especificidade, valor preditivo positivo e valor preditivo negativo de 90,9, 90,9, 90,9 e 90,9%, respectivamente. Enquanto a contagem dos valores de leucócitos, neutrófilos, linfócitos e PCR foi significantemente diferente entre os grupos de pacientes e controle (p<0,05), a contagem de plaquetas não foi (p>0,05).

Conclusão:

Os valores de VPM e RN/L sugerem que estes são parâmetros inflamatórios de acompanhamento rápido, barato e confiável, e que podem ser facilmente integrados à prática diária para o tratamento de APA, exceto pela contagem de plaquetas.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Peritonsillar Abscess / Lymphocyte Count / Mean Platelet Volume / Neutrophils Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Braz. j. otorhinolaryngol. (Impr.) Journal subject: Otolaryngology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Konya Education and Research Hospital/TR

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Full text: Available Index: LILACS (Americas) Main subject: Peritonsillar Abscess / Lymphocyte Count / Mean Platelet Volume / Neutrophils Type of study: Diagnostic study / Observational study / Prognostic study / Risk factors Limits: Adult / Female / Humans / Male Language: English Journal: Braz. j. otorhinolaryngol. (Impr.) Journal subject: Otolaryngology Year: 2016 Type: Article Affiliation country: Turkey Institution/Affiliation country: Konya Education and Research Hospital/TR