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Flavonoids from Capsella bursa-pastoris and their hepatoprotective activities in vitro
Ma, Qinge; Guo, Yongming; Wei, Rongrui; Sang, Zhipei; Liu, Wenmin; Gao, Li; Liu, Taotao.
  • Ma, Qinge; Nanyang Normal University. College of Chemistry and Pharmaceutical Engineering. Nanyang. CN
  • Guo, Yongming; Nanyang Normal University. College of Chemistry and Pharmaceutical Engineering. Nanyang. CN
  • Wei, Rongrui; Nanyang Normal University. College of Chemistry and Pharmaceutical Engineering. Nanyang. CN
  • Sang, Zhipei; Nanyang Normal University. College of Chemistry and Pharmaceutical Engineering. Nanyang. CN
  • Liu, Wenmin; Nanyang Normal University. College of Chemistry and Pharmaceutical Engineering. Nanyang. CN
  • Gao, Li; Nanyang Normal University. College of Chemistry and Pharmaceutical Engineering. Nanyang. CN
  • Liu, Taotao; Nanyang Normal University. College of Chemistry and Pharmaceutical Engineering. Nanyang. CN
Rev. bras. farmacogn ; 26(6): 710-713, Nov.-Dec. 2016. tab, graf
Article in English | LILACS | ID: biblio-829917
ABSTRACT
ABSTRACT Two new flavonoids (1 and 2), named 4',7-dihydroxy-5-hydroxymethyl-8-prenylflavonoid and 4',7-dihydroxy-5-hydroxymethyl-6,8-diprenylflavonoid, together with seven known flavonoids (3–9) were isolated from the aerial parts of Capsella bursa-pastoris (L.) Medik., Brassicaceae, for the first time. The chemical structures of the purified compounds (1–9) were identified by their spectroscopic data and references. Moreover, compounds (1–9) were evaluated for their hepatoprotective activities against D-galactosamine induced toxicity in WB-F344 cells by using a MTT colorimetric method. As a result, compounds 2, 3, 6, and 9 (10 µM) exhibited moderate hepatoprotective activities.

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Full text: Available Index: LILACS (Americas) Language: English Journal: Rev. bras. farmacogn Journal subject: Pharmacy Year: 2016 Type: Article Affiliation country: China Institution/Affiliation country: Nanyang Normal University/CN

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Full text: Available Index: LILACS (Americas) Language: English Journal: Rev. bras. farmacogn Journal subject: Pharmacy Year: 2016 Type: Article Affiliation country: China Institution/Affiliation country: Nanyang Normal University/CN