Sustitutos cutáneos bioingenierizados para el tratamiento de heridas cutáneas difíciles de curar / Cutaneous substitutes for cutaneous lesions which are unresponsive to conventional treatment
Rev. chil. dermatol
;
31(2): 145-150, 2015.
Article
in Spanish
| LILACS
| ID: biblio-836004
RESUMEN
Existe un aumento significativo de heridas cutáneas que no curan con terapias convencionales, situación preocupante tanto para la salud pública como para la economía mundial. Como posible solución se encuentra la ingeniería tisular cuyo fin es, mediante la generación de sustitutos cutáneos, entregar elementos capaces de reemplazar in vivo tejidos dañados, estimulando además la capacidad regenerativa intrínseca del paciente. Algunos productos han sido aprobados por la FDA (food and drug administration), los que han demostrado el cierre completo de heridas cutáneas refractarias a tratamientos habituales. De esta manera, la ingeniería tisular se considera actualmente como una alternativa terapéutica eficaz tanto para la cura de heridas cutáneas agudas como para heridas cutáneas crónicas, obteniéndose un balance costo-beneficio favorable a largo plazo para el paciente.
ABSTRACT
In recent years there has been a significant increase in skin lesions which do not heal with conventional therapies. This is a worrisome situation for both public health and global economy. One possible solution is tissue engineering which goal, is to generate substitute tissues that could be used to replace damaged ones in vivo, stimulating the patients intrinsic healing capacity. Some products have already been approved by the FDA (the Food and Drug Administration), and have already demonstrated complete closure of cutaneous lesions which are unresponsive to conventional treatment. Tissue engineering is considered an effective alternative therapy for acute and chronic lesions, and offer a favorable cost-benefit relationship in the long term.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Skin
/
Wound Healing
/
Biocompatible Materials
/
Skin, Artificial
/
Tissue Engineering
Limits:
Humans
Language:
Spanish
Journal:
Rev. chil. dermatol
Journal subject:
Dermatology
Year:
2015
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Hospital Clínico Universidad de Chile/CL
/
Universidad de Chile/CL
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