Management Strategies for Liver Fibrosis
Ann. hepatol
;
16(1): 48-56, Jan.-Feb. 2017. graf
Article
in English
| LILACS
| ID: biblio-838085
ABSTRACT
Abstract Liver fibrosis resulting from chronic liver injury are major causes of morbidity and mortality worldwide. Among causes of hepatic fibrosis, viral infection is most common (hepatitis B and C). In addition, obesity rates worldwide have accelerated the risk of liver injury due to nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH). Also liver fibrosis is associated with the consumption of alcohol, or autoimmune hepatitis and chronic cholangiophaties. The response of hepatocytes to inflammation plays a decisive role in the physiopathology of hepatic fibrosis, which involves the recruitment of both pro- and anti-inflammatory cells such as monocytes and macrophages. As well as the production of other cytokines and chemokines, which increase the stimulus of hepatic stellate cells by activating proinflammatory cells. The aim of this review is to identify the therapeutic options available for the treatment of the liver fibrosis, enabling the prevention of progression when is detected in time.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Liver Cirrhosis
/
Anti-Inflammatory Agents
Type of study:
Etiology study
/
Prognostic study
Limits:
Animals
/
Humans
Language:
English
Journal:
Ann. hepatol
Journal subject:
Gastroenterology
Year:
2017
Type:
Article
Affiliation country:
Mexico
Institution/Affiliation country:
Medica Sur Clinic/MX
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