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Treatment of acromegaly patients at the Federal University of Triângulo Mineiro (UFTM): Experience Report
de Fátima Borges, Maria; Lara, Beatriz Hallal Jorge; Tomé, Janaíne Machado; de Araújo, Leopoldo Prezia; Bugiga, Flávio Cesar Lucas; Sousa, Júlio Cláudio; Soares, Jacqueline Mendes Fonseca; Dezena, Roberto Alexandre; Ferreira, Beatriz Pires.
  • de Fátima Borges, Maria; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Lara, Beatriz Hallal Jorge; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Tomé, Janaíne Machado; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • de Araújo, Leopoldo Prezia; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Bugiga, Flávio Cesar Lucas; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Sousa, Júlio Cláudio; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Soares, Jacqueline Mendes Fonseca; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Dezena, Roberto Alexandre; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
  • Ferreira, Beatriz Pires; Universidade Federal do Triângulo Mineiro. Divisão de Endocrinologia e Metabolismo. Uberaba. BR
Clinics ; 72(4): 218-223, Apr. 2017. tab, graf
Article in English | LILACS | ID: biblio-840068
ABSTRACT

OBJECTIVE:

To evaluate the effectiveness of the treatment of acromegaly patients at the Federal University of Triangulo Mineiro.

METHODS:

Cross-sectional and retrospective study of thirty cases treated over a period of two decades.

RESULTS:

17 men (56.7%) aged 14-67 years and 13 women aged 14-86 years were analyzed. Twenty-one patients underwent transphenoidal surgery, whichwas associated with somatostatin receptor ligands in 11 patients (39.3%), somatostatin receptor ligands + radiotherapyin 5 patients (17.8%), radiotherapy in 3 patients (10.7%), and radiotherapy + somatostatin receptorligands + cabergoline in 1 patient (3.6%). Additionally, 2 patients underwent radiotherapy and surgeryalone. Six patients received somatostatin receptor ligands before surgery, and 2 were not treated due to refusal and death. Nine patients have died, and 20 are being followed; 13 (65%) have growth hormonelevels o1 ng/mL, and 11 have normal insulin-like growth factor 1 levels.

CONCLUSION:

The current treatment options enable patients seen in regional reference centers to achieve strict control parameters, which allows them to be treated close to their homes.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Acromegaly / Adenoma / Receptors, Somatostatin / Growth Hormone-Secreting Pituitary Adenoma Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Clinics Journal subject: Medicine Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Triângulo Mineiro/BR

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Full text: Available Index: LILACS (Americas) Main subject: Acromegaly / Adenoma / Receptors, Somatostatin / Growth Hormone-Secreting Pituitary Adenoma Type of study: Observational study / Prevalence study / Risk factors Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Clinics Journal subject: Medicine Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Triângulo Mineiro/BR