Vascular dysfunction in obesity: beneficial effects of aerobic exercise training in animal models
Motriz (Online)
;
23(spe): e101621, 2017. tab, Ilus
Article
in English
| LILACS
| ID: biblio-841858
ABSTRACT
Abstract Cardiovascular disease (CVD) is the leading cause of mortality in the world and several risk factors for developing CVD have been pointed out, including obesity and physical inactivity. Endothelial dysfunction as a consequence of metabolic and inflammatory disorders plays an important role in the onset of vascular complications in obesity. In addition, it is well established that aerobic exercises promote beneficial effects on CVD by increasing nitric oxide (NO) production or its bioavailability in human and experimental models. The interest in exercise studies increased significantly, with promising results. Considering the importance of this field, the purpose of this mini-review is to summarize the animal studies that investigated the physiological mechanisms of vascular dysfunction in obesity and how aerobic exercise training influenced these alterations.(AU)
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LILACS (Americas)
Main subject:
Cardiovascular Diseases
/
Exercise
/
Models, Animal
/
Obesity
Type of study:
Prognostic study
/
Risk factors
Limits:
Animals
Language:
English
Journal:
Motriz (Online)
Journal subject:
EducaÆo F¡sica e Treinamento
/
Medicina Esportiva
/
Medicina F¡sica e ReabilitaÆo
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Estadual de Campinas/BR
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