Síndrome metabólico e inflamación en adultos: un estudio poblacional / Association of C reactive protein levels with metabolic syndrome in adults: a population-based study
Rev. méd. Chile
;
144(10): 1239-1246, oct. 2016. tab
Article
in Spanish
| LILACS
| ID: biblio-845436
ABSTRACT
Background:
Metabolic syndrome is highly prevalent among adults in Chile and represents a health risk.Aim:
To determine the relationship between metabolic syndrome (MetS) and its components, with C reactive protein levels (CRP) as an inflammation marker. Material andMethods:
The population studied consisted of 736 individuals born in a hospital from Valparaíso Region, aged between 32-38 years at the time of the study. MetS was identified according to the Adult Treatment Panel (ATP) III guidelines and inflammation was measured using ultra-sensitive CRP. This parameter was classified as normal for values from 0 to 3 mg/L, high for values from 3.01 to 10 mg/L and very high for values > 10 mg/L.Results:
Median CRP was in the normal range (1.9 mg/L, interquartile range 0.7-5.2) and was higher among women than men (2.2 and 1.4 mg/L respectively, p < 0.01). Twenty seven percent of participants had MetS. One-fourth had high blood glucose values, one-third had high triglyceride levels and 28% had blood pressure values over those established as normal in MetS. Elevated waist circumference (WC) and low HDL cholesterol were found among almost 50% of participants. A relationship between MetS and high CRP was only found among men with an Odds ratio (OR) of 2.04 (95% confidence intervals (CI) 1.11-3.73). The same association was observed for high triglyceride levels with an OR of 2.02 (CI 1.17-3.49) and high WC with an OR of 3.89 (CI 2.06-7.36). Among women, the only relationship observed was between abdominal obesity and very high CRP with an OR of 2. 65 (CI 1.20-5.84).Conclusions:
Metabolic syndrome, high triglyceride levels, and abdominal obesity were associated with inflammation only in men.
Full text:
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Index:
LILACS (Americas)
Main subject:
C-Reactive Protein
/
Metabolic Syndrome
Type of study:
Etiology study
/
Practice guideline
/
Observational study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Chile
Language:
Spanish
Journal:
Rev. méd. Chile
Journal subject:
Medicine
Year:
2016
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
Universidad de Chile/CL
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