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Trombolisis intravenosa en cuadros imitadores de isquemia cerebral: experiencia de un centro / Thrombolysis in stroke mimics: experience in 10 cases
Brunser, Alejandro M; Hoppe, Arnold; Muñoz, Paula; Lavados, Pablo M; Illanes, Sergio; Díaz, Violeta; Olavarría, Verónica V.
  • Brunser, Alejandro M; Clínica Alemana de Santiago. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular. Santiago. CL
  • Hoppe, Arnold; Clínica Alemana de Santiago. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular. Santiago. CL
  • Muñoz, Paula; Clínica Alemana de Santiago. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular. Santiago. CL
  • Lavados, Pablo M; Clínica Alemana de Santiago. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular. Santiago. CL
  • Illanes, Sergio; Clínica Alemana de Santiago. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular. Santiago. CL
  • Díaz, Violeta; Clínica Alemana de Santiago. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular. Santiago. CL
  • Olavarría, Verónica V; Clínica Alemana de Santiago. Departamento de Medicina. Servicio de Neurología. Unidad de Tratamiento del Ataque Cerebrovascular. Santiago. CL
Rev. méd. Chile ; 144(10): 1266-1269, oct. 2016. tab
Article in Spanish | LILACS | ID: biblio-845440
ABSTRACT

Background:

The effectiveness of intravenous thrombolysis (IVT) in cerebral ischemia is time dependent. Stroke mimics (SM) are frequent in emergency rooms. The effort to reduce door to needle time, can lead to administer thrombolytics to SM.

Aim:

To describe the frequency and prognosis of SM treated with IVT. Material and

Methods:

Prospective analysis of all patients evaluated in a Chilean private clinic between December 2004 and July 2015 with a suspected acute ischemic stroke (AIS). We calculated the number of SM that were treated with IVT. In these patients, we analyzed the presence of symptomatic cerebral hemorrhage defined as the presence of a neurological deterioration of four points or more on the National Institute of Health Stroke Scale, the presence of extracranial bleeding according to Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries criteria and the patient’s functional status at three months by modified Rankin scale (MRS).

Results:

We evaluated 1,417 patients with suspected AIS, of which 240 (16.9%) were finally diagnosed as SM. A total of 197 patients were treated with IVT, of these 10 (5%) corresponded to SM. All SM patients treated with thrombolytic drugs were functionally independent at 3 months and showed no bleeding complications.

Conclusions:

Occasionally SM patients were treated with IVT. This treatment was not associated with bleeding complications and the prognosis of these patients at three months was favorable.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Brain Ischemia / Stroke / Fibrinolytic Agents Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2016 Type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Alemana de Santiago/CL

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Full text: Available Index: LILACS (Americas) Main subject: Brain Ischemia / Stroke / Fibrinolytic Agents Type of study: Etiology study / Observational study / Prognostic study / Risk factors Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: Spanish Journal: Rev. méd. Chile Journal subject: Medicine Year: 2016 Type: Article Affiliation country: Chile Institution/Affiliation country: Clínica Alemana de Santiago/CL