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Efeito de dentifrícios fluoretados e suplementados com nanopartículas de trimetafosfato de sódio sobre a desmineralização, remineralização e erosão dentária / Effect of fluoride toothpastes and supplemented with nano-sized sodium trimetaphosphate on enamel demineralization and remineralization and on dental erosion
Araçatuba; s.n; 2014. 159 p. tab, ilus, graf.
Thesis in English, Portuguese | LILACS, BBO | ID: biblio-867179
RESUMO
O objetivo deste estudo foi avaliar a capacidade de dentifrícios convencionais (1100 ppm F) suplementados com trimetafosfato de sódio micrométrico ou nanoparticulado (TMP; TMPnano), em reduzir a desmineralização (in vitro), promover a remineralização (in situ) e reduzir a erosão dentária (in vitro). No estudo de desmineralização, blocos de esmalte bovino (n = 96) selecionados pela dureza de superfície inicial (SHi) foram divididos em oito grupos de dentifrícios (n = 12) sem fluoreto e sem TMP (Placebo); 1100 ppm F (1100 ppm F); 1100 ppm F associado 1% TMP micrométrico e nanoparticulado (1100 1%TMP; 1100 1%TMPnano), 1100 ppm F associado a 3% TMP micrométrico e nanoparticulado (1100 3%TMP; 1100 3%TMPnano), 1110 ppm F associado a 6% TMP micrométrico e nanoparticulado (1100 6%TMP; 1100 6%TMPnano). Os blocos foram submetidos a ciclagem de pH durante cinco dias, sendo o tratamento com os respectivos dentifrícios realizados 2x/dia. A seguir, determinou-se a dureza de superfície final (SHf), perda mineral integrada (IML), diferencial da perda mineral integrada (ΔIML) e fluoreto (F) no esmalte. Os resultados foram submetidos à análise de variância seguida pelo teste Student-Newman-Keuls (p < 0,001). O grupo 1100 3%TMPnano apresentou a menor perda mineral (SHf, IML e ΔIML) seguido pelo grupo 1100 3%TMP (p < 0,001). O grupo 1100 3%TMPnano apresentou a maior concentração de F no esmalte, seguido pelo 1100 6%TMPnano (p < 0,001). Para o estudo de remineralização, blocos de esmalte bovinos (n = 192) foram selecionados pela dureza de superfície pós-desmineralização (SH1), e divididos em quatro grupos experimentais Placebo, 1100 ppm F, 1100 3% TMP micrométrico (1100 TMP), 1100 3% TMP nanoparticulado (1100 TMPnano). Doze voluntários utilizaram dispositivos palatinos, com quatro blocos de esmalte desmineralizados, durante três dias, sendo a escovação realizada 3x/dia. Após o período de remineralização determinou-se a porcentagem de recuperação de dureza de superfície (%SHR)...
ABSTRACT
The aim of this study was to evaluate the ability of conventional toothpaste (1100 ppm F) supplemented with micrometric or nano-sized sodium trimetaphosphate (TMP; TMPnano ), in reducing demineralization (in vitro), promote remineralization ( in situ ) and reduce erosion tooth (in vitro). In the study of demineralization of bovine enamel blocks (n = 96 ) selected by the initial surface hardness ( SHi ) were divided into eight groups of toothpaste (n = 12) without fluoride and without TMP (Placebo), 1100 ppm F (1100 ppm F) 1100 ppm F associated 1% TMP micrometric and nano-sized (1100 1%TMP; 1100 1%TMPnano), 1100 ppm F associated with 3% TMP micrometric and nano-sized (1100 3%TMP; 1100 3%TMPnano), 1110 ppm F associated with 6% TMP micrometric and nano-sized TMP (1100 6%TMP; 1100 6%TMPnano). The blocks were subjected to pH cycling for five days, and treatment with their toothpastes made 2x/day. Next, we determined the final surface hardness (SHf), integrated mineral loss (IML), differential integrated mineral loss (ΔIML) and fluoride (F) in the enamel. The results were subjected to analysis of variance followed by Student-Newman-Keuls test (p < 0.001). The group 1100 3 %TMPnano had the lowest mineral loss (SHF, IML and ΔIML) followed by 1100 3%TMP group (p < 0.001). The group 100 3%TMPnano showed a higher concentration of F in the enamel, followed by 1100 6%TMPnano (p < 0.001). For the study of remineralization of bovine enamel blocks (n = 192) were selected by the hardness of the surface after demineralization (SH1), and divided into four groups Placebo, 1100 ppm F, 1100 3 % TMP micrometric (1100 TMP) and 1100 3% TMP nano-sized (1100 TMPnano ). Twelve volunteers wore palatal appliances with four blocks of demineralized enamel, for three days, and brushing held 3x/day. After the period of remineralization determined the percentage of recovery of surface hardness (%SHR), recovery of integrated mineral loss (IMLR), and F ΔIML enamel. The %SHR, ΔIML and F were...
Subject(s)

Full text: Available Index: LILACS (Americas) Main subject: Phosphates / Tooth Erosion / Tooth Remineralization / Tooth Demineralization / Dental Enamel / Dentifrices / Nanoparticles / Fluorine Type of study: Controlled clinical trial Limits: Adult / Female / Humans / Male Language: English / Portuguese Year: 2014 Type: Thesis

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Full text: Available Index: LILACS (Americas) Main subject: Phosphates / Tooth Erosion / Tooth Remineralization / Tooth Demineralization / Dental Enamel / Dentifrices / Nanoparticles / Fluorine Type of study: Controlled clinical trial Limits: Adult / Female / Humans / Male Language: English / Portuguese Year: 2014 Type: Thesis