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Effect of preservatives on reactivity of fluoride with dental enamel
Arthur, Rodrigo; Tabchoury, Cínthia; Giancristófaro, Magda; Del Bel Cury, Altair Antoninha; Cury, Jaime Aparecido.
Affiliation
  • Arthur, Rodrigo; State University of Campinas. Faculty of Dentistry. Piracicaba. BR
  • Tabchoury, Cínthia; State University of Campinas. Faculty of Dentistry. Piracicaba. BR
  • Giancristófaro, Magda; State University of Campinas. Faculty of Dentistry. Piracicaba. BR
  • Del Bel Cury, Altair Antoninha; State University of Campinas. Faculty of Dentistry. Piracicaba. BR
  • Cury, Jaime Aparecido; State University of Campinas. Faculty of Dentistry. Piracicaba. BR
RGO (Porto Alegre) ; 55(4): 375-379, out.-dez. 2007. tab
Article in En | LILACS, BBO | ID: biblio-873498
Responsible library: BR1.1
Localization: BR541.1
ABSTRACT

Objectives:

Evaluate the effect of preservatives, usually present in mouthrinse formulations, on fluoride reactivity with enamel.

Methods:

Ninety-six bovine enamel slabs (4 x 4 x 2 mm), 48 sound and 48 with caries-like lesions, were longitudinally sectioned through the center. Half of each slab was kept as control and the other one subjected during 10 min to 0.05% NaF solutions containing or not 0.2% methylparaben, 0.02% propylparaben or 0.35% benzoate. Two consecutive layers of enamel were removed from all slabs, by acid etching and fluoride acid extracted was determined with specific electrode.

Results:

Fluoride concentration in the half treated was subtracted from that found in the control and expressed as μg F/cm2 of enamel surface. Fluoride reactivity with sound enamel was not affected by the preservatives (P > 0.05), but methylparaben increased the reactivity of 0.05% NaF solution with carious one (P < 0.05).

Conclusion:

The results suggest that methylparaben may improve fluoride reactivity with enamel, presenting caries-like lesions, but further studies are necessary to evaluate the mechanism.
RESUMO

Objetivos:

Avaliar o efeito de conservantes, usualmente presentes em enxagüatórios bucais, na reatividade do fluoreto com o esmalte dental.

Métodos:

Noventa e seis blocos de esmalte bonivo (4 x 4 x 2 mm), 48 hígidos e 48 com lesão artificial de cárie, foram seccionados longitudinalmente ao meio. Uma metade de cada bloco foi mantida como controle e a outra reagiu, durante 10 min, com solução de NaF 0,05% contendo ou não metilparabeno 0,2%, propilparabeno 0,02% ou benzoato 0,35%. Duas camadas consecutivas de esmalte foram removidas de todos os blocos por ataque ácido e o fluoreto presente nesse extrato ácido foi determinado com eletrodo específico.

Resultados:

A concentração de fluoreto da metade tratada foi subtraída daquela presente nos controles e expressa em μg F/cm2 da superfície de esmalte. A reatividade do fluoreto com esmalte hígido não foi afetada pelos conservantes (p>0,05), mas o metilparabeno aumentou a reatividade da solução de NaF 0,05% com o esmalte cariado (p<0,05).

Conclusão:

Os resultados sugerem que o metilparabeno pode aumentar a reatividade do fluoreto com o esmalte com lesão de cárie, masestudos adicionais são necessários para avaliar esse mecanismo.
Subject(s)
Full text: 1 Index: LILACS Main subject: Dental Enamel / Fluorides / Mouthwashes Limits: Animals Language: En Journal: RGO (Porto Alegre) Journal subject: ODONTOLOGIA Year: 2007 Type: Article
Full text: 1 Index: LILACS Main subject: Dental Enamel / Fluorides / Mouthwashes Limits: Animals Language: En Journal: RGO (Porto Alegre) Journal subject: ODONTOLOGIA Year: 2007 Type: Article