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CLINICAL, MAMMOGRAPHIC AND HISTOPATHOLOGICAL CORRELATION OF BREAST CANCER IN WOMEN AGED BETWEEN 50 AND 70 YEARS / Correlação clínica, mamográfica e histopatológica do câncer mamário em mulheres com idade entre 50 e 70 anos
Vieira, Mariana Meira; Alvares, Beatriz Regina; Almeida, Orlando José de; Jales, Rodrigo Menezes.
  • Vieira, Mariana Meira; School of Medical Sciences, Universidade Estadual de Campinas (Unicamp). Campinas. BR
  • Alvares, Beatriz Regina; Department of Radiology, School of Medical Sciences, Unicamp. Campinas. BR
  • Almeida, Orlando José de; Radiology Section, Center for Full Attention to Women's Health, Unicamp. Campinas. BR
  • Jales, Rodrigo Menezes; Department of Tocoginecology, Unicamp. Campinas. BR
Mastology (Impr.) ; 27(2): [96-101], abr. - jun. 2017.
Article in English | LILACS | ID: biblio-875919
ABSTRACT
Objective: To correlate the clinical, mammographic and histopathological findings of women aged between 50 and 70 years old who were diagnosed with breast cancer and were assisted between 1998 and 2013 at the Mastology Outpatient Clinic of the Center for Full Attention to Women's Health in Universidade Estadual de Campinas (CAISM-Unicamp). Methods: This was a cross-sectional and retrospective study, in which the medical records and mammograms of 160 women were analyzed, a sufficient sample size for the statistical analysis. The variables used for comparison were the clinical, mammographic and histopathological findings, analyzed through descriptive and associative statistics. Results: Of the 160 cases analyzed, 76.9% were symptomatic, and the main clinical findings included palpable nodule (68.1%) and skin alterations (30%). The prevalent mammographic presentations in asymptomatic women were microcalcifications (48.7%), nodules (43.2%) and architectural distortion (8.1%). Regarding the histological type, 81.3% presented invasive ductal carcinoma (IDC) and 10.7%, ductal carcinoma in situ (DCIS). Conclusion: The present study showed that there was a predominance of symptomatic women with mammographic presentation of spiculated nodules and histological type of IDC. In the other patients with lesions detected in the screening test, pleomorphic microcalcifications were prevalent as the main finding of DCIS. Diagnostic mammography was the main form of detection of breast cancer, which may represent the lack of access of these women to screening or early detection of malignant lesions. This reveals the need to improve control actions and care protocols of these patients.
RESUMO
Objetivo: Correlacionar os achados clínicos, mamográficos e histopatológicos de mulheres na faixa etária entre 50 e 70 anos que tiveram diagnóstico de câncer mamário e foram atendidas, entre 1998 e 2013, no Ambulatório de Mastologia do Centro de Atenção Integral à Saúde da Mulher da Universidade Estadual de Campinas (CAISM-Unicamp). Métodos: Trata-se de um estudo de corte transversal e retrospectivo, no qual foram analisados os prontuários e as mamografias de 160 mulheres, tamanho amostral suficiente para a análise estatística. As variáveis usadas para comparação foram os achados clínicos, mamográficos e histopatológicos, analisados por meio da estatística descritiva e associativa. Resultados: Entre os 160 casos analisados, 76,9% eram sintomáticos e os principais achados clínicos incluíram nódulo palpável (68,1%) e alterações de pele (30%). As apresentações mamográficas prevalentes nas mulheres assintomáticas foram microcalcificações (48,7%), nódulos (43,2%) e distorção arquitetural (8,1%). Com relação ao tipo histológico, 81,3% apresentaram carcinoma ductal invasivo (CDI) e 10,7%, carcinoma ductal in situ (CDIS). Conclusão: O presente trabalho evidenciou que houve uma predominância de mulheres sintomáticas, com apresentação mamográfica de nódulos espiculados e tipo histológico de CDI. Já nas demais pacientes com lesões detectadas no exame de rastreamento predominaram as microcalcificações pleomórficas como o principal achado do CDIS. A mamografia diagnóstica foi a principal forma de detecção do câncer mamário, podendo representar a falta de acesso dessas mulheres aos exames de rastreamento ou à não detecção precoce das lesões malignas, o que revela a necessidade de melhorar as ações de controle e os protocolos de atendimento dessas pacientes.


Full text: Available Index: LILACS (Americas) Type of study: Practice guideline / Observational study / Prevalence study / Risk factors / Screening study Language: English Journal: Mastology (Impr.) Journal subject: Neoplasias da Mama Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Department of Radiology, School of Medical Sciences, Unicamp/BR / Department of Tocoginecology, Unicamp/BR / Radiology Section, Center for Full Attention to Women's Health, Unicamp/BR / School of Medical Sciences, Universidade Estadual de Campinas (Unicamp)/BR

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Full text: Available Index: LILACS (Americas) Type of study: Practice guideline / Observational study / Prevalence study / Risk factors / Screening study Language: English Journal: Mastology (Impr.) Journal subject: Neoplasias da Mama Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Department of Radiology, School of Medical Sciences, Unicamp/BR / Department of Tocoginecology, Unicamp/BR / Radiology Section, Center for Full Attention to Women's Health, Unicamp/BR / School of Medical Sciences, Universidade Estadual de Campinas (Unicamp)/BR