The cross-talk between the kidney and the gut: implications for chronic kidney diseaseThe cross-talk between the kidney and the gut: implications for chronic kidney disease
Nutrire Rev. Soc. Bras. Aliment. Nutr
;
42: 1-14, Dec. 2017. tab, ilus
Article
in English
| LILACS
| ID: biblio-880613
ABSTRACT
In recent decades, special attention has been given to the potential association between the gut ecosystem and chronic diseases. Several features and complications of chronic kidney disease (CKD) may induce an unbalanced gut environment, leading to unfavorable consequences for a patient's health. The first section of this review is dedicated to a description of some aspects of gut microbiota and intestinal barrier physiology. The following section explores the impact of CKD on the gut ecosystem and intestinal barrier, particularly the association with uremic toxins, inflammation, and immunodeficiency. Finally, the review describes the state of the art of potential therapies with prebiotics, probiotics, and synbiotics employed to modulate the gut environment and to reduce the generation of colon-derived uremic toxins in CKD.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Renal Insufficiency, Chronic
/
Gastrointestinal Microbiome
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Nutrire Rev. Soc. Bras. Aliment. Nutr
Journal subject:
Nutritional Sciences
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Federal University of São Paulo/BR
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