Your browser doesn't support javascript.
loading
Analysis of IL-10 in HIV-1 patients with chronic periodontitis in northern Brazil
Menezes, Silvio Augusto Fernandes de; Menezes, Tatiany Oliveira de Alencar; Rodrigues, Tânia Maria de Souza; Nogueira, Brenna Magdalena Lima; Fonseca, Ricardo Roberto de Souza.
  • Menezes, Silvio Augusto Fernandes de; University Center of Pará. School of Dentistry. Departament of periodontology. Belém. BR
  • Menezes, Tatiany Oliveira de Alencar; University Center of Pará. School of Dentistry. Departament of patients with special needs. Belém. BR
  • Rodrigues, Tânia Maria de Souza; University Center of Pará. School of Dentistry. Departament of periodontology. Belém. BR
  • Nogueira, Brenna Magdalena Lima; University Center of Pará. School of Dentistry. Departament of endodontics. Belém. BR
  • Fonseca, Ricardo Roberto de Souza; University Center of Pará. School of Dentistry. Departament of periodontology. Belém. BR
Braz. j. oral sci ; 16: e17072, jan.-dez. 2017. tab
Article in English | LILACS, BBO | ID: biblio-883655
ABSTRACT
The objective of this study was to investigate the levels of IL-10 in the gingival crevicular fluid in HIV-1 positive patients with chronic periodontitis and to compare with HIV-1 negative patients with chronic periodontitis, also to correlate clinical periodontal parameters, viral load and count of CD4 + and CD8 + lymphocytes (LTCD4 + and LTCD8 +).

Methods:

33 patients were selected and splitted into two groups 16 HIV-1 positive patients and 17 HIV-1 negative patients and all with chronic periodontitis. The clinical periodontal parameters recorded were Probing Depth (PD) and Clinical Attachment Level (CAL); the sistemical parameters LTCD4 +, LTCD8 + and viral load were analized by the gingival crevicular fluid collected from all patients. Enzymelinked immunosorbent assay (ELISA) was used to determine the concentrations of Interleukin (IL)-10. For the statistical analysis the Student t, Mann-Whitney and Spearman tests were performed. IL-10 levels were significantly lower in both patients groups.

Results:

There was statistical difference betwen groups for probing depth (p=0.015) and clinical attachment level (p=0.011), no significant correlation was found among the analyzed variables.

Conclusion:

The IL-10 levels in HIV-1 positive patients had no influence in periodontal and medical parameters (AU)
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Gingival Crevicular Fluid / HIV-1 / Interleukin-10 / Chronic Periodontitis Limits: Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. j. oral sci Journal subject: Dentistry Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: University Center of Pará/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Gingival Crevicular Fluid / HIV-1 / Interleukin-10 / Chronic Periodontitis Limits: Female / Humans / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. j. oral sci Journal subject: Dentistry Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: University Center of Pará/BR