Analysis of IL-10 in HIV-1 patients with chronic periodontitis in northern Brazil
Braz. j. oral sci
;
16: e17072, jan.-dez. 2017. tab
Article
in English
| LILACS, BBO
| ID: biblio-883655
ABSTRACT
The objective of this study was to investigate the levels of IL-10 in the gingival crevicular fluid in HIV-1 positive patients with chronic periodontitis and to compare with HIV-1 negative patients with chronic periodontitis, also to correlate clinical periodontal parameters, viral load and count of CD4 + and CD8 + lymphocytes (LTCD4 + and LTCD8 +). Methods:
33 patients were selected and splitted into two groups 16 HIV-1 positive patients and 17 HIV-1 negative patients and all with chronic periodontitis. The clinical periodontal parameters recorded were Probing Depth (PD) and Clinical Attachment Level (CAL); the sistemical parameters LTCD4 +, LTCD8 + and viral load were analized by the gingival crevicular fluid collected from all patients. Enzymelinked immunosorbent assay (ELISA) was used to determine the concentrations of Interleukin (IL)-10. For the statistical analysis the Student t, Mann-Whitney and Spearman tests were performed. IL-10 levels were significantly lower in both patients groups.Results:
There was statistical difference betwen groups for probing depth (p=0.015) and clinical attachment level (p=0.011), no significant correlation was found among the analyzed variables.Conclusion:
The IL-10 levels in HIV-1 positive patients had no influence in periodontal and medical parameters (AU)
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Gingival Crevicular Fluid
/
HIV-1
/
Interleukin-10
/
Chronic Periodontitis
Limits:
Female
/
Humans
/
Male
Country/Region as subject:
South America
/
Brazil
Language:
English
Journal:
Braz. j. oral sci
Journal subject:
Dentistry
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
University Center of Pará/BR
Similar
MEDLINE
...
LILACS
LIS