Effects of the essential oil of Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. on healing and tissue repair after partial Achilles tenotomy in rats
Acta cir. bras
;
32(6): 449-458, June 2017. tab, graf
Article
in English
| LILACS
| ID: biblio-886204
ABSTRACT
Abstract Purpose:
To investigate the cellular response to injury, analyzing histopathologic changes associated with increased cellularity, degeneration and disorganization of collagen fibers.Methods:
Thirty wistar rats were divided in two groups after partial Achilles tenotomy the right hind paw were treated with the essential oil of Alpinia zerumbet (EOAz), diluted to 33% (0.3 mL kg-1), and the left hind paw received sunflower oil for 3, 14, 30 and 90 days. Statistical significance was determined using a Chi-square and Pearson Correlation qualitative variables test. Moreover, Mann-Whitney U-test test for comparison between different groups of the same cell, one-way ANOVA, and Tukey's test of quantitative measurement.Results:
A decrease hyperemia (p < 0.001) was observed in the acute phase of inflammatory cell number (p < 0.001), whereas sub-acute phase was marked by significant correlation with macrophages in fibroblasts (r = 0.17, p = 0.03), with probable induction a dense and modeled tissue. At chronic phase, it was found an increase in the number of fibroblasts and a higher percentage of type I collagen fibers (78%) compared with control collagen fibers (55%).Conclusion:
Oil of Alpinia zerumbet stimulated the process of maturation, organization and tissue repair which gave it greater resistance.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Achilles Tendon
/
Wound Healing
/
Oils, Volatile
/
Alpinia
Type of study:
Qualitative research
Limits:
Animals
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Tiradentes/BR
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