A prospective randomized study of the inflammatory responses to multiport and singleport laparoscopic hysterectomies
Acta cir. bras
;
32(7): 576-586, July 2017. tab, graf
Article
in English
| LILACS
| ID: biblio-886217
ABSTRACT
Abstract Purpose:
To evaluate the inflammatory responses induced by laparoscopic hysterectomies with multiport and singleport approaches.Methods:
This was a pilot prospective randomized study that included 42 women candidates for hysterectomy at School of Medicine, Hospital das Clínicas, USP. The patients were randomized to two groups MP-TLH (total laparoscopic hysterectomy with 3 abdominal incisions), and SP-TLH (total laparoscopic hysterectomy with a single umbilical incision).We evaluated the inflammatory response (via CRP, IL-6, IL-10, TNFα, VEGF and leukogram assessments), surgical time, postoperative pain, blood loss and surgical complications in both groups.Results:
Both techniques were similar regarding C-reactive protein (p=.666), IL-6 (p=.833), IL-10 (p=.420), TNF-α(p=.098), VEGF (p=.092) and the leukogram (p=.712) measures. The operative time was significantly longer in the SP-TLH group than in the MP-TLH group (p=.001). The pain evaluation was similar in both groups (p=.170). Hemoglobin variation and the aspirated blood volume were similar in both groups (p=.493 and p=.347). There were no major complications.Conclusions:
Multiport and singleport laparoscopic approaches are both safe methods for hysterectomy. Although SP-TLH resulted in a significantly longer operative time than MP-TLH, no differences were observed between the groups in inflammatory responses, blood loss and postoperative pain.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Biomarkers
/
Hysterectomy
/
Inflammation
Type of study:
Controlled clinical trial
/
Diagnostic study
/
Observational study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Acta cir. bras
Journal subject:
General Surgery
/
Procedimentos Cir£rgicos Operat¢rios
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade de São Paulo/BR
Similar
MEDLINE
...
LILACS
LIS