Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
An. bras. dermatol
;
92(3): 404-406, May-June 2017. graf
Article
in English
| LILACS
| ID: biblio-886970
ABSTRACT
Abstract Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatologic diseases and has been reported as a rare cause of acute generalized exanthematous pustulosis. A 42-year-old female presented with pustular lesions on the skin surface with erythema, facial edema, and occasional atypical target-like lesions after 21 days of treatment with 200mg/day hydroxychloroquine for rheumatoid arthritis, diagnosed one month previously. We report a case with acute generalized exanthematous pustulosis induced by hydroxychloroquine and treated with dapsone and systemic corticosteroid.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Antirheumatic Agents
/
Acute Generalized Exanthematous Pustulosis
/
Hydroxychloroquine
Type of study:
Diagnostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2017
Type:
Article
Affiliation country:
Turkey
Institution/Affiliation country:
Okmeydani Training and Research Hospital/TR
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