Granulomatous slack skin: a rare subtype of mycosis fungoides
An. bras. dermatol
;
92(5): 694-697, Sept.-Oct. 2017. graf
Article
in English
| LILACS
| ID: biblio-887025
ABSTRACT
Abstract We report a case of granulomatous slack skin, a rare and indolent subtype of mycosis fungoides. It affects mainly men between the third and fourth decades. It is characterized by hardened and erithematous plaques that mainly affect flexural areas and become pedunculated after some years. Histological examination shows a dense infiltrate of small atypical lymphocytes involving the dermis (and sometimes the subcutaneous tissue) associated with histiocytic and multinucleated giant cells containing lymphocytes and elastic fibers (lymphophagocytosis and elastophagocytosis, respectively). Patients affected by this entity can develop secondary lymphomas. There are several but little effective therapeutic modalities described. Despite the indolent behavior of granulomatous slack skin, its early recognition and continuous monitoring by a dermatologist becomes essential for its management and prevention of an unfavorable outcome.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Skin Neoplasms
/
Lymphoma, T-Cell, Cutaneous
Limits:
Adult
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Instituto Lauro de Souza Lima (ILSL)/BR
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