Moderate to severe psoriasis treatment challenges through the era of biological drugs
An. bras. dermatol
;
92(5): 668-674, Sept.-Oct. 2017. tab
Article
in English
| LILACS
| ID: biblio-887045
ABSTRACT
Abstract: Biological therapy has revolutionized moderate to severe psoriasis treatment. However, despite being more effective than conventional systemic treatments, some patients do not respond or lose response to biotechnological treatments or develop drug-antibodies, interfering with its safety and efficacy. There are also clinical forms of the disease and patient profiles for which is pending further scientific evidence for more sustained therapeutic interventions. The continuous and more detailed knowledge of psoriasis pathophysiology has allowed identifying new therapeutic targets, which is expected to help overcome the challenges of individualized psoriasis treatment.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Psoriasis
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2017
Type:
Article
Affiliation country:
Portugal
Institution/Affiliation country:
São João Hospital Center/PT
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