Your browser doesn't support javascript.
loading
Photodynamic action of the red laser on Propionibacterium acnes
Ramos, Rogério Rodrigo; Paiva, Jeferson Leandro de; Gomes, José Paulo Franco dos Santos; Boer, Nagib Pezati; Godoy, José Maria Pereira de; Batigalia, Fernando.
  • Ramos, Rogério Rodrigo; Universidade Brasil. Department of Human Anatomy. Fernandópolis. BR
  • Paiva, Jeferson Leandro de; Universidade Brasil. Department of Human Anatomy. Fernandópolis. BR
  • Gomes, José Paulo Franco dos Santos; Universidade Brasil. Department of Human Anatomy. Fernandópolis. BR
  • Boer, Nagib Pezati; Universidade Brasil. Department of Human Anatomy. Fernandópolis. BR
  • Godoy, José Maria Pereira de; Universidade Brasil. Department of Human Anatomy. Fernandópolis. BR
  • Batigalia, Fernando; Universidade Brasil. Department of Human Anatomy. Fernandópolis. BR
An. bras. dermatol ; 92(5): 622-625, Sept.-Oct. 2017. tab, graf
Article in English | LILACS | ID: biblio-887046
ABSTRACT
Abstract

Background:

Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species.

Objective:

To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro.

Method:

The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals.

Results:

It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Study

limitations:

Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria.

Conclusion:

Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Photochemotherapy / Propionibacterium acnes / Photosensitizing Agents / Methylene Blue Limits: Humans Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Brasil/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Photochemotherapy / Propionibacterium acnes / Photosensitizing Agents / Methylene Blue Limits: Humans Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Brasil/BR