Photodynamic action of the red laser on Propionibacterium acnes
An. bras. dermatol
;
92(5): 622-625, Sept.-Oct. 2017. tab, graf
Article
in English
| LILACS
| ID: biblio-887046
ABSTRACT
Abstract Background:
Photodynamic therapy is a therapeutic modality that has consolidated its activity in the photooxidation of organic matter, which arises from the activity of reactive oxygen species.Objective:
To evaluate the effect of red laser 660nm with the photosensitizer methylene blue on Propionibacterium acnes in vitro.Method:
The experimental design was distributed into four groups (1 - control group without the application of light and without photosensitizer, 2 - application of light, 3 - methylene blue without light, and 4 - methylene blue with light). Tests were subjected to red laser irradiation 660nm by four cycles of 5 minutes at 3-minute intervals.Results:
It was evidenced the prominence of the fourth cycle (20 minutes) groups 2, 3 and 4. Studylimitations:
Despite the favorable results, the laser irradiation time photosensitizer associated with methylene blue were not sufficient to to completely inhibit the proliferation of bacteria.Conclusion:
Further studies in vitro are recommended to enable the clinical application of this photosensitizer in photodynamic therapy.
Full text:
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Index:
LILACS (Americas)
Main subject:
Photochemotherapy
/
Propionibacterium acnes
/
Photosensitizing Agents
/
Methylene Blue
Limits:
Humans
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2017
Type:
Article
Affiliation country:
Brazil
Institution/Affiliation country:
Universidade Brasil/BR
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