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Diffuse cutaneous melanosis: rare complication of metastatic melanoma
Amaral, Ana Cristina Vervloet do; Diniz, Lucia Martins; Lucas, Elton Almeida; Capeli, Rafaela Lorenzon de Aragão.
  • Amaral, Ana Cristina Vervloet do; Private practice. Vitória. BR
  • Diniz, Lucia Martins; Private practice. Vitória. BR
  • Lucas, Elton Almeida; Private practice. Vitória. BR
  • Capeli, Rafaela Lorenzon de Aragão; Private practice. Vitória. BR
An. bras. dermatol ; 92(5,supl.1): 62-64, 2017. graf
Article in English | LILACS | ID: biblio-887083
ABSTRACT
Abstract Diffuse cutaneous melanosis is a rare complication of metastatic melanoma related to a worse prognosis. There are few cases reported in the literature. Its pathogenesis has not been completely elucidated, although studies have suggested certain mechanisms for its occurrence. It is clinically manifested as a blue-gray discoloration of the skin and mucous membranes in a cephalo caudal progression and usually associated with melanuria. Skin and mucosa histopathology reveals only the presence of melanophages in the dermis, mainly perivascular, and free interstitial melanin. We report the case of a 68-year-old male with metastatic melanoma, diffuse hyperpigmentation of the skin and melanuria.
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Full text: Available Index: LILACS (Americas) Main subject: Skin Neoplasms / Melanoma / Melanosis Type of study: Prognostic study Limits: Humans / Male Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Private practice/BR

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Full text: Available Index: LILACS (Americas) Main subject: Skin Neoplasms / Melanoma / Melanosis Type of study: Prognostic study Limits: Humans / Male Language: English Journal: An. bras. dermatol Journal subject: Dermatology Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Private practice/BR