Metastatic Crohn's disease despite infliximab therapy
An. bras. dermatol
;
92(5,supl.1): 104-106, 2017. graf
Article
in English
| LILACS
| ID: biblio-887087
ABSTRACT
Abstract Metastatic Crohn's disease is a rare extraintestinal manifestation of Crohn's disease. It is characterized by polymorphic skin lesions formed by non-caseating granulomas located on anatomical sites distant from the gastrointestinal tract. We report a rare case of metastatic Crohn's disease, simultaneously displaying multiple clinically heterogeneous cutaneous lesions, in a patient with previously diagnosed Crohn's disease in remission due to anti-TNF-α use. This case highlights the need for high clinical suspicion and early biopsy in the setting of a patient with Crohn's disease and persistent skin lesions, even under biologic therapy. Furthermore, it reinforces the need of monitoring of the serum level of infliximab, increasing the dose in case it is low or undetectable.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Gastrointestinal Agents
/
Crohn Disease
/
Erythema
/
Infliximab
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2017
Type:
Article
Affiliation country:
Portugal
Institution/Affiliation country:
Centro Hospitalar e Universitário de Coimbra/PT
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