Orofacial granulomatosis and diet therapy: a review of the literature and two clinical cases
An. bras. dermatol
;
93(1): 80-85, Jan.-Feb. 2018. tab, graf
Article
in English
| LILACS
| ID: biblio-887135
ABSTRACT
Abstract Orofacial granulomatosis is a nonspecific term that contains a wide variety of granulomatous entities, which share a clinical and histopathological presentation. It manifests as persistent or recurrent orofacial swelling, amongst other findings. Idiopathic orofacial granulomatosis, characterized by an absence of systemic granulomatous disease, is a diagnosis of exclusion. The main differential diagnosis is Crohn's disease. Its pathogenesis is unknown, however, it seems to be immune-mediated. Patch-test sensitivity to multiple allergens is well documented. Currently, therapeutic options consider restrictive diets, topical, intralesional, and systemic agents. First-line therapy is currently a matter of debate. We present a review of the value of diet therapy in this syndrome, along with two illustrative cases.
Full text:
Available
Index:
LILACS (Americas)
Main subject:
Granulomatosis, Orofacial
Type of study:
Diagnostic study
Limits:
Adolescent
/
Adult
/
Humans
/
Male
Language:
English
Journal:
An. bras. dermatol
Journal subject:
Dermatology
Year:
2018
Type:
Article
Affiliation country:
Chile
Institution/Affiliation country:
University of Chile/CL
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