Effectiveness of the retreatment of patients with multibacillary leprosy and episodes of erythema nodosum leprosum and/or persistent neuritis: a single-center experience
An. bras. dermatol
; An. bras. dermatol;93(2): 181-184, Mar.-Apr. 2018. graf
Article
in En
| LILACS
| ID: biblio-887190
Responsible library:
BR1.1
ABSTRACT
Abstract Background:
Erythema nodosum leprosum may appear before, during or after treatment of leprosy and is one of the main factors for nerve damage in patients. When it occurs or continues to occur after treatment, it may indicate disease recurrence and a new treatment may be instituted again.Objective:
To evaluate the retreatment of patients with multibacillary leprosy who underwent standard treatment with multidrug therapy, but developed or continued to present reactions of erythema nodosum leprosum and/or neuritis 3-5 years after its end.Method:
For this objective, a new treatment was performed in 29 patients with multibacillary leprosy who maintained episodes of erythema nodosum and/or neuritis 3-5 years after conventional treatment.Results:
In general, we observed that 27 (93.10%) had no more new episodes after a follow up period of eight months to five years. In five of these patients the reason for the retreatment was the occurrence of difficult-to-control neuritis, and that has ceased to occur in all of them. Studylimitations:
Small number of patients..Conclusion:
In the cases observed, retreatment was an effective measure to prevent the occurrence of erythema nodosum leprosum and/or persistent neuritis.Key words
Full text:
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Index:
LILACS
Main subject:
Leprosy, Lepromatous
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Erythema Nodosum
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Leprosy, Multibacillary
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Neuritis
Type of study:
Evaluation_studies
Limits:
Female
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Humans
/
Male
Language:
En
Journal:
ABD: Anais brasileiros de dermatologia
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An Bras Dermatol
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An. bras. dermatol
/
An. bras. dermatol. (Online)
/
Anais brasileiros de dermatologia (Impresso)
Journal subject:
DERMATOLOGIA
Year:
2018
Type:
Article