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Quality of life in Parkinson's disease patients: progression markers of mild to moderate stages / Qualidade de vida de indivíduos com doença de Parkinson: marcadores da progressão da fase leve para moderada
Moreira, Raissa Carla; Zonta, Marise Bueno; Araújo, Ana Paula Serra de; Israel, Vera Lúcia; Teive, Hélio A G.
  • Moreira, Raissa Carla; Universidade Federal do Paraná. Curitiba. BR
  • Zonta, Marise Bueno; Universidade Federal do Paraná. Curitiba. BR
  • Araújo, Ana Paula Serra de; Universidade Federal do Paraná. Curitiba. BR
  • Israel, Vera Lúcia; Universidade Federal do Paraná. Curitiba. BR
  • Teive, Hélio A G; Universidade Federal do Paraná. Curitiba. BR
Arq. neuropsiquiatr ; 75(8): 497-502, Aug. 2017. tab
Article in English | LILACS | ID: biblio-888312
ABSTRACT
ABSTRACT Objective To investigate which factors are associated with the quality of life decline in Parkinson's disease patients from mild to moderate stages. Methods The Unified Parkinson's Disease Rating Scale and Parkinson's Disease Questionnaire-39 were used to evaluate clinical/functional data and the quality of life. Results The markers of clinical/functional worsening were drooling (p < 0.004), need for assistance with hygiene (p = 0.02), greater freezing frequency (p = 0.042), bradykinesia (p = 0.031), greater intensity of the resting tremor (p = 0.035) and "pill rolling" (p = 0.001). The decline in quality of life was related to stigma (p = 0.043), greater impairment in cognition (p = 0.002), mobility (p = 0.013) and for daily living activities (p = 0.05), and was considered more significant in men, married, older individuals, and those with a longer time of disease. Conclusions The quality of life worsening markers at the moderate stage were related to stigma, worsening of cognition, and to greater impairment in mobility and daily living activities.
RESUMO
RESUMO Objetivo Verificar os fatores relacionados ao declínio clínico/funcional e de Qualidade de Vida de indivíduos com Doença de Parkinson, da fase leve para moderada. Métodos Foram utilizadas as escalas Unified Parkinson's Disease Rating Scale and Parkinson's Disease Questionnaire-39 (UPDRS e PDQ-39) para avaliação clínico/funcional e de qualidade de vida Resultados Os marcadores de piora clínico/funcional na fase moderada foram sialorréia (p < 0,004), necessidade de ajuda para higiene (p = 0,02), maior frequência do "freezing" (p = 0,042), bradicinesia (p = 0,031) e maior intensidade do tremor de repouso (p = 0,035) e bater dos dedos (p = 0,001). O declínio da qualidade de vida esteve relacionado ao estigma (p = 0,043), ao maior comprometimento da cognição (p = 0,002), da mobilidade (p = 0,013) e da independência para realizar as atividade de vida diária (AVD's) (p = 0,05), sendo mais importante nos homens, nos casados, nos indivíduos com maior idade e naqueles com maior tempo de evolução da doença. Conclusão Os marcadores de piora da qualidade de vida na fase moderada estiveram relacionados ao estigma, à piora da cognição, ao maior comprometimento para mobilidade e AVD's.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Parkinson Disease / Quality of Life Type of study: Observational study / Prevalence study / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Paraná/BR

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Full text: Available Index: LILACS (Americas) Main subject: Parkinson Disease / Quality of Life Type of study: Observational study / Prevalence study / Risk factors Limits: Aged / Aged80 / Female / Humans / Male Language: English Journal: Arq. neuropsiquiatr Journal subject: Neurology / Psychiatry Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal do Paraná/BR