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High prevalence of hepatitis E virus antibodies in Sao Paulo, Southeastern Brazil: analysis of a group of blood donors representative of the general population
Passos-Castilho, Ana Maria; Reinaldo, Mônica Renata; Sena, Anne de; Granato, Celso F H.
Affiliation
  • Passos-Castilho, Ana Maria; Federal University of Sao Paulo. Division of Infectious Diseases. Sao Paulo. BR
  • Reinaldo, Mônica Renata; Federal University of Sao Paulo. Division of Infectious Diseases. Sao Paulo. BR
  • Sena, Anne de; Federal University of Sao Paulo. Division of Infectious Diseases. Sao Paulo. BR
  • Granato, Celso F H; Federal University of Sao Paulo. Division of Infectious Diseases. Sao Paulo. BR
Braz. j. infect. dis ; 21(5): 535-539, Sept.-Oct. 2017. tab, graf
Article in En | LILACS | ID: biblio-888907
Responsible library: BR1.1
ABSTRACT
Abstract Brazil is a non-endemic country for hepatitis E virus (HEV) infection with seroprevalence from 1% to 4% in blood donors and the general population. However, data on seroprevalence of HEV in the country are still limited. This study evaluated the prevalence of past or present HEV infection in a group of blood donors representative of the general population of the city of Sao Paulo, Southeastern Brazil. Serum samples from 500 blood donors were tested from July to September 2014 by serological and molecular methods. Anti-HEV IgG antibodies were detected in 49 (9.8%) subjects and categorized age groups revealed an age-dependent increase of HEV seroprevalence. Among the anti-HEV IgG positive subjects, only 1 had anti-HEV IgM while none tested positive for HEV-RNA. The present data demonstrate a higher seroprevalence of anti-HEV IgG than previously reported in the region.
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Full text: 1 Index: LILACS Main subject: Blood Donors / Hepatitis E virus / Hepatitis E Type of study: Diagnostic_studies / Prevalence_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Braz. j. infect. dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Type: Article

Full text: 1 Index: LILACS Main subject: Blood Donors / Hepatitis E virus / Hepatitis E Type of study: Diagnostic_studies / Prevalence_studies / Risk_factors_studies Limits: Adolescent / Adult / Aged / Female / Humans / Male Country/Region as subject: America do sul / Brasil Language: En Journal: Braz. j. infect. dis Journal subject: DOENCAS TRANSMISSIVEIS Year: 2017 Type: Article