Your browser doesn't support javascript.
loading
A cross-sectional study assessing the pharyngeal carriage of Neisseria meningitidis in subjects aged 1-24 years in the city of Embu das Artes, São Paulo, Brazil
Weckx, Lily Yin; Puccini, Rosana Fiorini; Machado, Antónia; Gonçalves, Maria Gisele; Tuboi, Suely; Barros, Eliana de; Devadiga, Raghavendra; Ortega-Barria, Eduardo; Colindres, Romulo.
  • Weckx, Lily Yin; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Puccini, Rosana Fiorini; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Machado, Antónia; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Gonçalves, Maria Gisele; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Tuboi, Suely; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Barros, Eliana de; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Devadiga, Raghavendra; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Ortega-Barria, Eduardo; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
  • Colindres, Romulo; Universidade Federal de São Paulo. Departamento de Pediatria. São Paulo. BR
Braz. j. infect. dis ; 21(6): 587-595, Nov.-Dec. 2017. tab, graf
Article in English | LILACS | ID: biblio-888918
ABSTRACT
ABSTRACT Meningococcal carriage is a prerequisite for invasive infection. This cross-sectional study assessed the pharyngeal carriage prevalence in healthy subjects aged 1-24 years in Embu das Artes city, São Paulo, Brazil. Pharyngeal swabs were examined for the presence of Neisseria meningitidis. The isolates were tested for different serogroups using agglutination and polymerase chain reaction. A logistic regression model assessed any independent association between Neisseria meningitidis carriage and various risk factors. A total of 87/967 subjects (9%, 95% Confidence Interval (CI) 7.3-11.0) tested positive for N. meningitidis 6.2% (95% CI 3.8-9.4) in 1-4 years, 8.5% (95% CI 5.1-13.0) in 5-9 years, 12.5% (95% CI 7.8-18.6) in 10-14 years, 12.6% (95% CI 7.4-19.7) in 15-19 years and 9% (95% CI 4.9-14.9) in 20-24 years age groups. Highest carriage prevalence was observed in adolescents 10-19 years old. Serogroup C was predominant (18.4%) followed by serogroup B (12.6%). The 15-19 years age group showed a significant association between number of household members and carriers of N. meningitidis. This cross-sectional study is the first in Brazil to evaluate meningococcal carriage prevalence and associated factors in a wide age range.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Pharynx / Carrier State / Meningococcal Infections / Neisseria meningitidis Type of study: Diagnostic study / Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São Paulo/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Pharynx / Carrier State / Meningococcal Infections / Neisseria meningitidis Type of study: Diagnostic study / Etiology study / Observational study / Prevalence study / Prognostic study / Risk factors Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male Country/Region as subject: South America / Brazil Language: English Journal: Braz. j. infect. dis Journal subject: Communicable Diseases Year: 2017 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Federal de São Paulo/BR