Your browser doesn't support javascript.
loading
Two novel Mg(II)-based and Zn(II)-based complexes: inhibiting growth of human liver cancer cells
Liu, N; Ding, D; Wang, L; Zhao, H; Zhu, L; Geng, X.
  • Liu, N; First Affiliated Hospital of Anhui Medical University. Department of Critical Care Medicine. Hefei. CN
  • Ding, D; First Affiliated Hospital of Anhui Medical University. Department of Critical Care Medicine. Hefei. CN
  • Wang, L; First Affiliated Hospital of Anhui Medical University. Department of Critical Care Medicine. Hefei. CN
  • Zhao, H; First Affiliated Hospital of Anhui Medical University. Department of Critical Care Medicine. Hefei. CN
  • Zhu, L; First Affiliated Hospital of Anhui Medical University. Department of Critical Care Medicine. Hefei. CN
  • Geng, X; First Affiliated Hospital of Anhui Medical University. Department of Critical Care Medicine. Hefei. CN
Braz. j. med. biol. res ; 51(2): e6929, 2018. tab, graf
Article in English | LILACS | ID: biblio-889031
ABSTRACT
Two new Mg(II)-based and Zn(II)-based coordination polymers, {[Mg3(BTB)(DMA)4](DMA)2}n (1, H3BTB=1,3,5-benzenetrisbenzoic acid, DMA=N,N-dimethylacetamide) and {(H2NMe2)2[Zn3(BTB)2(OH)(Im)](DMF)9(MeOH)7}n (2, Im=imidazole, DMF=N,N-dimethylformamide), have been successfully synthesized and structurally characterized under solvothermal conditions. 1 contains a linear [Mg3(COO)6] cluster that connected by the fully deprotonated BTB3- ligands to give a kgd-type 2D bilayer structure; 2 represents a microporous 3D pillar-layered system based on the binuclear Zn units and pillared Im ligands, which shows a (3,5)-connected hms topological net. In addition, in vitro anticancer activities of compounds 1 and 2 on 4 human liver cancer cells (HB611, HHCC, BEL-7405 and SMMC-7721) were determined.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Benzimidazoles / Metal-Organic Frameworks / Liver Neoplasms / Antineoplastic Agents Type of study: Evaluation studies Limits: Humans Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 2018 Type: Article Affiliation country: China Institution/Affiliation country: First Affiliated Hospital of Anhui Medical University/CN

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Benzimidazoles / Metal-Organic Frameworks / Liver Neoplasms / Antineoplastic Agents Type of study: Evaluation studies Limits: Humans Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 2018 Type: Article Affiliation country: China Institution/Affiliation country: First Affiliated Hospital of Anhui Medical University/CN