Your browser doesn't support javascript.
loading
Performance during a strenuous swimming session is associated with high blood lactate: pyruvate ratio and hypoglycemia in fasted rats
Travassos, PB; Godoy, G; De Souza, HM; Curi, R; Bazotte, RB.
  • Travassos, PB; Universidade Estadual de Maringá. Departamento de Farmacologia e Terapêutica. Maringá. BR
  • Godoy, G; Universidade Estadual de Maringá. Departamento de Farmacologia e Terapêutica. Maringá. BR
  • De Souza, HM; Universidade Estadual de Maringá. Departamento de Farmacologia e Terapêutica. Maringá. BR
  • Curi, R; Universidade Estadual de Maringá. Departamento de Farmacologia e Terapêutica. Maringá. BR
  • Bazotte, RB; Universidade Estadual de Maringá. Departamento de Farmacologia e Terapêutica. Maringá. BR
Braz. j. med. biol. res ; 51(5): e7057, 2018. tab, graf
Article in English | LILACS | ID: biblio-889076
ABSTRACT
The aim of this study was to investigate the effect of lactatemia elevation and glycemia reduction on strenuous swimming performance in fasted rats. Three rats were placed in a swimming tank at the same time. The first rat was removed immediately (control group) and the remaining ones were submitted to a strenuous swimming session. After the second rat was exhausted (Exh group), the third one was immediately removed from the water (Exe group). According to the period of time required for exhaustion, the rats were divided into four groups low performance (3-7 min), low-intermediary performance (8-12 min), high-intermediary performance (13-17 min), and high performance (18-22 min). All rats were removed from the swimming tanks and immediately killed by decapitation for blood collection or anesthetized for liver perfusion experiments. Blood glucose, lactate, and pyruvate concentrations, blood lactate/pyruvate ratio, and liver lactate uptake and its conversion to glucose were evaluated. Exhaustion in low and low-intermediary performance were better associated with higher lactate/pyruvate ratio. On the other hand, exhaustion in high-intermediary and high performance was better associated with hypoglycemia. Lactate uptake and glucose production from lactate in livers from the Exe and Exh groups were maintained. We concluded that there is a time sequence in the participation of lactate/pyruvate ratio and hypoglycemia in performance during an acute strenuous swimming section in fasted rats. The liver had an important participation in preventing hyperlactatemia and hypoglycemia during swimming through lactate uptake and its conversion to glucose.
Subject(s)


Full text: Available Index: LILACS (Americas) Main subject: Swimming / Lactic Acid / Pyruvic Acid / Hypoglycemia / Liver Type of study: Risk factors Limits: Animals Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Maringá/BR

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Index: LILACS (Americas) Main subject: Swimming / Lactic Acid / Pyruvic Acid / Hypoglycemia / Liver Type of study: Risk factors Limits: Animals Language: English Journal: Braz. j. med. biol. res Journal subject: Biology / Medicine Year: 2018 Type: Article Affiliation country: Brazil Institution/Affiliation country: Universidade Estadual de Maringá/BR